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Keywords: Heparan sulfate proteoglycan
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Journal Articles
Journal: Development
Development (2016) 143 (1): 75–87.
Published: 1 January 2016
... modulating structural and functional synaptogenesis, including the GPI-anchored heparan sulfate proteoglycan (HSPG) Wnt co-receptor Dally-like protein (Dlp), cognate receptor Frizzled-2 (Frz2) and Wingless (Wg) ligand. Loss of either Mmp1 or Mmp2 reciprocally misregulates Dlp at the synapse, with normal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (20): 4621–4633.
Published: 15 October 2005
...,regulatory mechanisms are likely to play a crucial role in controlling cell migration and axonal pathfinding. Heparan sulfate proteoglycans (HSPGs) carry long chains of differentially modified sugar residues that have been proposed to encode specific information for nervous system development. Here, we show...
Journal Articles
Journal: Development
Development (2004) 131 (9): 1927–1938.
Published: 1 May 2004
...Douglas J. Bornemann; Jason E. Duncan; William Staatz; Scott Selleck; Rahul Warrior Studies in Drosophila and vertebrate systems have demonstrated that heparan sulfate proteoglycans (HSPGs) play crucial roles in modulating growth factor signaling. We have isolated mutations in sister of tout velu...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2129–2138.
Published: 15 May 2003
... movements in Xenopus and zebrafish. Heparan sulfate proteoglycans (HSPGs) are known as modulators of intercellular signaling, and are required for gastrulation movements in vertebrates. However, the function of HSPGs is poorly understood. We analyze the function of Xenopus glypican 4 (Xgly4), which...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1515–1522.
Published: 15 April 2003
... protein and Dpp signal transduction is potentiated by Dally, a cell-surface heparan sulfate proteoglycan, during assembly of several adult tissues. However, the molecular mechanism by which the Dpp morphogen gradient is established and maintained is poorly understood. We show evidence that Dally regulates...