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Keywords: Hematopoietic stem and progenitor cell
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Journal Articles

The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling

Open Access
Ying Li, Can Li, Mengyao Liu, Shicheng Liu, Feng Liu, Lu Wang
Journal: Development
Development (2023) 150 (21): dev201890.
https://doi.org/10.1242/dev.201890
Published: 24 October 2023
...Ying Li; Can Li; Mengyao Liu; Shicheng Liu; Feng Liu; Lu Wang ABSTRACT In vertebrates, the earliest hematopoietic stem and progenitor cells (HSPCs) are derived from a subset of specialized endothelial cells, hemogenic endothelial cells, in the aorta-gonad-mesonephros region through endothelial...
View articletitled, The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling
Open the PDF for The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling in another window
Includes: Supplementary data
Journal Articles

Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis

Open Access
Peng Lv, Shuai Gao, Feng Liu
Journal: Development
Development (2023) 150 (20): dev201690.
https://doi.org/10.1242/dev.201690
Published: 15 June 2023
...Peng Lv; Shuai Gao; Feng Liu ABSTRACT The crosstalk between hematopoietic lineages is important for developmental hematopoiesis. However, the role of primitive red blood cells (RBCs) in the formation of definitive hematopoietic stem and progenitor cells (HSPCs) is largely unknown. Primitive RBC...
View articletitled, Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis
Open the PDF for Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis in another window
Includes: Supplementary data
Journal Articles

DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling

Open Access
Yan Li, Chao Tang, Fan Liu, Caiying Zhu, Feng Liu, Ping Zhu, Lu Wang
Journal: Development
Development (2022) 149 (10): dev200390.
https://doi.org/10.1242/dev.200390
Published: 25 May 2022
...Yan Li; Chao Tang; Fan Liu; Caiying Zhu; Feng Liu; Ping Zhu; Lu Wang ABSTRACT The earliest hematopoietic stem and progenitor cells (HSPCs) are generated from the ventral wall of the dorsal aorta, through endothelial-to-hematopoietic transition during vertebrate embryogenesis. Notch signaling...
View articletitled, DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling
Open the PDF for DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling in another window
Includes: Supplementary data