..., hippocampus development is known to be regulated by the hem organizer. Here, we have identified that, in birds, Wnt7b secreted from the hem is sufficient for inducing the expression of hippocampal markers. Furthermore, we have demonstrated that a microRNA, miR-19b, which is selectively excluded from the hem...

...Geeta Godbole; Ashwin S. Shetty; Achira Roy; Leora D'Souza; Bin Chen; Goichi Miyoshi; Gordon Fishell; Shubha Tole ABSTRACT During forebrain development, a telencephalic organizer called the cortical hem is crucial for inducing hippocampal fate in adjacent cortical neuroepithelium. How the hem...