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Keywords: Hedgehog signalling
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Journal Articles
Journal: Development
Development (2021) 148 (7): dev189258.
Published: 15 April 2021
... GPCRs may crosstalk with the Hh pathway in mammals. References Apionishev , S. , Katanayeva , N. M. , Marks , S. A. , Kalderon , D. and Tomlinson , A. ( 2005 ). Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction . Nat. Cell Biol. 7...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev192443.
Published: 17 February 2021
...: James Briscoe Competing interests The authors declare no competing or financial interests. 4 5 2020 14 1 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: Loss of Gpr161 leads to reduced PKA activity and derepression of Hedgehog signalling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev186411.
Published: 21 December 2020
... with cellular homeostasis and animal development. This theme was central to Suzanne Eaton's research in the fruit fly, Drosophila . Here, we discuss her work on membrane lipid homeostasis in changing environments and on functions for lipids in the Hedgehog signalling pathway. We further highlight lipoproteins...
Journal Articles
Journal: Development
Development (2019) 146 (9): dev172502.
Published: 2 May 2019
... subventricular origins of forebrain oligodendrogenesis . Front. Neurosci.   10 , 107 . 10.3389/fnins.2016.00107 Balordi , F. and Fishell , G. ( 2007 ). Hedgehog signaling in the subventricular zone is required for both the maintenance of stem cells and the migration of newborn neurons . J...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (3): 367–372.
Published: 1 February 2016
... 10 2015 15 12 2015 © 2016. Published by The Company of Biologists Ltd 2016 Summary: This poster article reviews our current understanding of Hedgehog signalling mechanisms in metazoan development. Drosophila Hedgehog signalling Vertebrate Hedgehog (Hh) signalling...
Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (15): 3261–3272.
Published: 1 August 2011
... limb mesenchyme results in polydactyly and in brachydactyly and a failure of subperisoteal bone formation, defects that are attributable to abnormal sonic hedgehog and Indian hedgehog signalling, respectively. Like talpid 3 chicken limbs, the mutant mouse limbs are syndactylous with uneven digit...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 655–664.
Published: 15 February 2009
... ciliogenesis and Hh signalling. † Author for correspondence (e-mail: cat24@bath.ac.uk ) * These authors contributed equally to this work 11 12 2008 © 2009. 2009 Primary cilia Centrosome Hedgehog signalling Ciliopathies Talpid3 Chicken Neural tube Embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (2): 237–247.
Published: 15 January 2008
... formation Wnt canonical signalling β-catenin Tcf/Lef1 transcription factors Hedgehog signalling Gli transcription factors Gli3 locus Mouse Chick Distinct types of neuron are generated along the dorsal ventral (DV) axis of the developing spinal cord. Neurons that process and relay sensory...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 2903–2912.
Published: 15 August 2007
... blot analysis. We conclude that Evc is an intracellular component of the hedgehog signal transduction pathway that is required for normal transcriptional activation of Ihh target genes. Evc +/- mice have no discernable defects. Offspring from heterozygous Evc +/- crosses were genotyped at E18.5...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (13): 2545–2554.
Published: 1 July 2001
... that OLPs in the telencephalon, possibly even some of those in the cortex, develop under the influence of SHH in the ventral forebrain. ‡Author for correspondence (e-mail: w.richardson@ucl.ac.uk ) 10 4 2001 © 2001. 2001 Telencephalon Hedgehog signalling Oligodendrocyte Rat...