1-20 of 35
Keywords: Hedgehog signaling
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2020) 147 (17): dev185678.
Published: 02 September 2020
... pathway by both cell-autonomous and non-autonomous mechanisms. Intestinal stem cell Wnt signaling Mesenchymal cell Hedgehog signaling MAPK Adult stem cells are crucial for cell proliferation and regeneration of differentiated cells during tissue homeostasis. The intestinal epithelium...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (10): dev166892.
Published: 15 May 2019
... important roles in development and disease. Cholesterol Hedgehog signaling Morphogen Patched Primary cilium Smoothened Research on the HH pathway has uncovered unexpected principles in signal transduction: the covalent modification of ligands by cholesterol, the use of primary cilia to...
Journal Articles
Journal: Development
Development (2018) 145 (24): dev165381.
Published: 18 December 2018
... after 12 months. References Ahn , S. and Joyner , A. L. ( 2004 ). Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning . Cell   118 , 505 - 516 . 10.1016/j.cell.2004.07.023 Akiyama , H. , Kim , J.-E. , Nakashima , K...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev165068.
Published: 19 November 2018
... enhancers in midline expression . Dev. Biol.   301 , 578 - 589 . 10.1016/j.ydbio.2006.11.004 Evangelista , M. , Tian , H. and de Sauvage , F. J. ( 2006 ). The hedgehog signaling pathway in cancer . Clin. Cancer Res.   12 , 5924 - 5928 . 10.1158/1078-0432.CCR-06-1736 Favor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (18): dev167221.
Published: 21 September 2018
... patterning Hedgehog signaling Cardin–Weintraub motif 30 4 2018 24 7 2018 © 2018. Published by The Company of Biologists Ltd 2018 http://www.biologists.com/user-licence-1-1/ Hedgehog morphogen family members are essential determinants of metazoan body plans. In Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (18): dev164830.
Published: 20 September 2018
... response of cells to positive hedgehog signaling during mouse limb patterning . Cell   118 , 505 - 516 . 10.1016/j.cell.2004.07.023 Andre , P. , Song , H. , Kim , W. , Kispert , A. and Yang , Y. ( 2015 ). Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev162586.
Published: 06 August 2018
... – Hh mediates gill slit formation and Nodal establishes their left-right position. Pharyngeal patterning Gill slit development Nodal signaling Hedgehog signaling Branchiostoma Summary: In cephalochordates (amphioxus), the late gastrula/early neurula stage is critical for the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (14): 2584–2594.
Published: 15 July 2017
.... and Kalderon , D. ( 2015 ). Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila . Development   142 , 931 - 942 . 10.1242/dev.112904 Zhu , C.-H. and Xie , T. ( 2003 ). Clonal expansion of ovarian germline stem cells during niche formation in...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (8): 1544–1553.
Published: 15 April 2017
... ). IFT56 TTC26 Cilia Intraflagellar transport IFTB Hedgehog signaling Microtubule structure Summary: IFT56 is key for the integrity and function of intraflagellar transport in cilia, and, consequently, for vertebrate development. © 2017. Published by The Company of Biologists Ltd 2017...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1317–1327.
Published: 01 April 2017
... and branching, but did not phenocopy transgenic expression of activated smoothened ( SmoM2 ). The epithelium showed no evidence of canonical hedgehog signaling, and hyperproliferation was not blocked by smoothened (SMO) inhibition, suggesting a non-canonical function of PTCH1. Consistent with this...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1165–1176.
Published: 01 April 2017
... Barresi , M. J. , Stickney , H. L. and Devoto , S. H. ( 2000 ). The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity . Development   127 , 2189 - 2199 . Becerra , J. , Junqueira , L. C. U...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (5): 856–865.
Published: 01 March 2017
... dysregulates transcription of the Hedgehog-related genes wrt-8 and grl-16 , the overexpression of which is sufficient to induce the axonal defects. Deficiency of either wrt-8 or grl-16 , or reduced expression of homologs of genes promoting Hedgehog signaling, restores correct axon guidance in jmjd-1.2 mutants...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (21): 3944–3955.
Published: 01 November 2016
... Perron , M. ( 2004 ). Hedgehog signaling in vertebrate eye development: a growing puzzle . Cell. Mol. Life Sci.   61 , 899 - 910 . 10.1007/s00018-003-3370-7 Bayer , M. , Fischer , J. , Kremerskothen , J. , Ossendorf , E. , Matanis , T. , Konczal , M. , Weide , T...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (12): 2194–2202.
Published: 15 June 2015
... , R. J. , Houtzager , V. M. , Cullum , R. , Montpetit , R. , Metzler , M. , Simpson , E. M. , Roy , S. , Hayden , M. R. , Hoodless , P. A. , et al. ( 2006 ). Hippi is essential for node cilia assembly and Sonic hedgehog signaling . Dev. Biol. 300 , 523 - 533...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1651–1660.
Published: 01 May 2015
...Jinling Liu; Huiqing Zeng; Aimin Liu Hedgehog signaling is crucial for vertebrate development and physiology. Gli2, the primary effector of Hedgehog signaling, localizes to the tip of the primary cilium, but the importance of its ciliary localization remains unclear. We address the roles of Gli2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (18): 3445–3457.
Published: 15 September 2014
... ( joynera@mskcc.org ) Competing interests The authors declare no competing financial interests. © 2014. Published by The Company of Biologists Ltd 2014 Adult stem cells Hedgehog signaling Homeostasis During vertebrate development, hedgehog (HH) signaling plays an essential role...
Journal Articles
Journal: Development
Development (2014) 141 (15): 3003–3012.
Published: 01 August 2014
... found disruptions in Hedgehog signaling. Post-translational processing of GLI2 and GLI3 was aberrant in the developing facial prominences. Although both GLI2 and GLI3 processing were disrupted in talpid 2 mutants, only GLI3 activator levels were significantly altered in the nucleus. Through additional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (18): 3848–3857.
Published: 15 September 2013
.... , Miura T. , Shiota K. , Ishibashi M. ( 2008 ). Hedgehog signaling is involved in development of the neocortex . Development 135 , 2717 – 2727 . Lanford P. J. , Lan Y. , Jiang R. , Lindsell C. , Weinmaster G. , Gridley T. , Kelley M. W. ( 1999...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2371–2380.
Published: 01 July 2012
... ( Fig. 6B ). We note that the ihha hu2131 allele contains a nonsense mutation; hence, the apparent decrease in ihha expression might be the consequence of nonsense mediated mRNA degradation ( Chang et al., 2007 ). Dermal bone Hedgehog signaling Modularity Morphogenesis...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (11): 2389–2398.
Published: 01 June 2011
... authors declare no competing financial interests. 17 3 2011 © 2011. 2011 Bmp signaling Cardiac arterial pole Cardiac progenitors Hedgehog signaling Second heart field tbx1 Zebrafish In chick and mouse, cardiac progenitors are organized bilaterally in the epiblast on...
Includes: Supplementary data