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Keywords: Hairy
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Journal: Development
Development (2014) 141 (1): 63–72.
Published: 1 January 2014
... of genetic and pharmacological manipulations in zebrafish to show that during neurogenesis FGF activity occurs as a gradient along the anterior-posterior axis of the dorsal midbrain and directs spatially dynamic expression of the Hairy gene her5 . As FGF activity diminishes during development, Her5 is lost...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (9): 1994–2004.
Published: 1 May 2013
... levels, nuclear migration, apical cell constriction and an acceleration of the furrow. We find that these roles are distinct from the bHLH protein Hairy (H), which we show restricts atonal ( ato ) expression ahead of the furrow. Secondary furrow initiation along the dorsal and ventral margins is blocked...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (22): 4261–4270.
Published: 15 November 2012
... M. F. , Monuki E. S. , Millen K. J. ( 2006 ). The roof plate regulates cerebellar cell-type specification and proliferation . Development 133 , 2793 - 2804 . Cui Y. ( 2005 ). Hairy is a cell context signal controlling Notch activity . Dev. Growth Differ. 47 , 609...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (11): 2681–2692.
Published: 1 June 2004
..., a pattern that depends on periodic expression of the hairy gene ( h ) and the proneural genes achaete ( ac ) and scute ( sc ). Expression of ac in longitudinal stripes in prepupal leg discs defines the positions of the mechanosensory bristle rows. The ac / sc expression domains are delimited by the Hairy...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (24): 5903–5914.
Published: 15 December 2003
... the same cDNA library under less stringent conditions (50°C). We thus isolated an additional Hairy homologue that we denominated Amphi-hairyE. Amphi-hairyA to Amphi-hairyD plus an additional Amphi-hairyF genes were also identified through an EST project of gastrula and neurula stages( Panopoulou et...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (8): 1591–1604.
Published: 15 April 2003
... expression of genes defining MHB identity. We further show that expression of the zebrafish bHLH Hairy/E(spl)-related factor Her5 prefigures and then precisely delineates the IZ throughout embryonic development. Using morpholino knock-down and conditional gain-of-function assays, we demonstrate that Her5...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (10): 1793–1804.
Published: 15 May 2001
... in these cells. Mutation of ref-1 also affects the fate of other epidermal cells in distinct AP body regions. ref-1 encodes a protein with two basic helix-loop-helix domains distantly related to those of the hairy/Enhancer of split family. ref-1 , and another hairy homolog, lin-22 , regulate similar cell fate...
Journal Articles
Journal: Development
Development (1999) 126 (13): 2891–2899.
Published: 1 July 1999
... and specify diverse cell types by creating unique local environments which establish the expression of locally acting genes. This process is exemplified by the patterning of leg microchaete rows. hairy ( h ) is expressed in a spatially restricted manner in the leg imaginal disc and functions to position adult...
Journal Articles
Journal: Development
Development (1997) 124 (15): 2875–2888.
Published: 1 August 1997
... lineages rather than V5-like lineages. lin-22 activity is also required to prevent additional neurons from being produced by one branch of the V5 lineage. We find that the lin-22 gene exhibits homology to the Drosophila gene hairy , and that lin-22 activity represses neural development within the V5...
Journal Articles
Journal Articles
Journal: Development
Development (1994) 120 (10): 2945–2955.
Published: 1 October 1994
...James A. Langeland; Sherwin F. Attai; Kathy Vorwerk; Sean B. Carroll ABSTRACT We present a genetic and molecular analysis of two hairy ( h ) pair-rule stripes in order to determine how gradients of gap proteins position adjacent stripes of gene expression in the posterior of Drosophila embryos. We...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 118 (1): 255–266.
Published: 1 May 1993
...Michael Lardelli; David Ish-Horowicz ABSTRACT The hairy ( h ) segmentation gene of Drosophila regulates segmental patterning of the early embryo, and is expressed in a set of anteroposterior stripes during the blastoderm stage. We have used a set of h gene deletions to study the h promoter...
Journal Articles
Journal: Development
Development (1993) 117 (2): 585–596.
Published: 1 February 1993
...James A. Langeland; Sean B. Carroll ABSTRACT The hairy (h) gene is one of two pair-rule loci whose striped expression is directly regulated by combinations of gap proteins acting through discrete upstream regulatory fragments, which span several kilobases. We have undertaken a comparative study...
Journal Articles
Journal Articles
Journal: Development
Development (1990) 110 (3): 759–767.
Published: 1 November 1990
...-rule gene hairy . The eve and hairy expression patterns overlap but are out of register and the cells of maximal overlap form the anterior margin of the polarized eve stripe. We propose that the relative placement of the eve and hairy stripes may be an important factor in the initiation of segment...