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1-2 of 2
Keywords: HSPGs
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Journal Articles
Wei-Ling Chang, Che-Wei Chang, Yu-Yun Chang, Hsin-Ho Sung, Ming-Der Lin, Shu-Chuan Chang, Chung-Hao Chen, Chia-Wei Huang, Kuei-Shu Tung, Tze-Bin Chou
Journal:
Development
Development (2013) 140 (13): 2798–2807.
Published: 1 July 2013
... proteoglycans (HSPGs). Mutations in the tumor suppressor genes EXT1 and EXT2 disturb HSPG biosynthesis and cause multiple osteochondroma (MO). How EXT1 and EXT2 traffic within the Golgi complex is not clear. Here, we show that Rotini (Rti), the Drosophila GOLPH3, regulates the retrograde trafficking of EXTs...
Includes: Supplementary data
Journal Articles
HB-EGF function in cardiac valve development requires interaction with heparan sulfate proteoglycans
Free
Journal:
Development
Development (2010) 137 (13): 2205–2214.
Published: 1 July 2010
... sulfate proteoglycans (HSPGs) to properly function in this process. In developing valves, HB-EGF is synthesized in endocardial cells but accumulates in the mesenchyme by interacting with HSPGs. Disrupting the interaction between HB-EGF and HSPGs in an ex vivo model of endocardial cushion explants resulted...
Includes: Supplementary data
