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Keywords: HSPC300
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Journal Articles
Journal:
Development
Development (2006) 133 (6): 1091–1100.
Published: 15 March 2006
... of actin filaments by the Arp2/3 complex requires the presence of an activator such as a member of the Scar/WAVE family. In mammalian cells, a multiprotein complex consisting of WAVE, PIR121/Sra-1, Nap1, Abi-2 and HSPC300 mediates responsiveness of WAVE to upstream regulators such as Rac. Essential roles...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2003) 130 (4): 753–762.
Published: 15 February 2003
... mother cell divisions. Together, these observations indicate that all three Brk genes act in a common pathway in which each Brk gene has a distinct function. Recent work demonstrating a function for the mammalian homolog of BRK1 (HSPC300) in activation of Arp2/3-dependent actin polymerization implicates...
