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Keywords: HNF6
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Journal Articles
The onecut transcription factor HNF6 is required for normal development of the biliary tract
Available to PurchaseFrédéric Clotman, Vincent J. Lannoy, Michael Reber, Silvia Cereghini, David Cassiman, Patrick Jacquemin, Tania Roskams, Guy G. Rousseau, Frédéric P. Lemaigre
Journal:
Development
Development (2002) 129 (8): 1819–1828.
Published: 15 April 2002
... the intrahepatic and extrahepatic bile ducts, and the gallbladder. The transcription factors that control the development of the biliary tract are unknown. Previous work has shown that the onecut transcription factor HNF6 is expressed in hepatoblasts and in the gallbladder primordium. We now show that HNF6 is also...
Journal Articles
Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function
Available to PurchaseMaureen Gannon, Michael K. Ray, Karla Van Zee, Francisco Rausa, Robert H. Costa, Christopher V. E. Wright
Journal:
Development
Development (2000) 127 (13): 2883–2895.
Published: 1 July 2000
...Maureen Gannon; Michael K. Ray; Karla Van Zee; Francisco Rausa; Robert H. Costa; Christopher V. E. Wright ABSTRACT We used transgenesis to explore the requirement for downregulation of hepatocyte nuclear factor 6 (HNF6) expression in the assembly, differentiation, and function of pancreatic islets...
