... transgene which expressed a transcript encoding an HMG-box transcription factor ( Jiménez et al., 2000 ). The maternal and zygotic fet phenotypes were successfully rescued by a single copy of the same transgene. Rescued fet flies developed wild-type wings and produced eggs with wild-type dorsal...

... insight, the gene was cloned by chromosome walking. CRABS CLAW encodes a putative transcription factor containing a zinc finger and a helix-loop-helix domain. The latter resembles the first two helices of the HMG box, known to bind DNA. At least five other genes of Arabidopsis carry the same combination...

...-acid DNA-binding domain known as the HMG box. Partial clones for the first three Sox genes (a1-a3) were isolated by homology to the HMG box of the testis-determining gene Sry and are now termed Sox-1, Sox-2 and Sox-3. Sox-3 is highly conserved amongst mammalian species and is located on the X...

... by Company of Biologists 1993 TCF-1 LEF-1 transcription factors HMG box T cell differentiation mouse In recent years, a number of T lymphocyte-specific enhancers have been identified that control transcription of structural T cell genes (reviewed in Clevers and Owen, 1991 ). This has...