..., a putative transcription factor that functions redundantly with CeMyoD(HLH-1) in striated body wall muscle (BWM) fate specification in the C. elegans postembryonic mesoderm. fozi-1 encodes a novel nuclear-localized protein with motifs characteristic of both transcription factors and actin-binding proteins...

.... elegans Myod homolog HLH-1 acts downstream of mls-2 to specify M-derived coelomocyte cell fates. Thus MLS-2 functions in a cell type-specific manner to regulate both cell proliferation and cell fate specification. * Author for correspondence (e-mail: [email protected] ) 6 7 2005 ©2005...

...-muscle phenotype had lost the hlh-1 + transgene in the early M lineage ( Fig. 5 ). By contrast, all animals with a wild-type number of vulval muscles carried the array in some or all cells from the M lineage. In some cases, CeMyoD could be lost late in the M lineage (in vulval muscles...

... elegans identified a single family member, hlh-1 , which is expressed in striated muscles and their clonal precursors. We have isolated a null allele of hlh-1 following chemical mutagenesis. Animals homozygous for the null mutation produce contractile body-wall muscles, although muscle contractions...