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Keywords: HIF1
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Journal Articles

HIF1α regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis

Roy Amarilio, Sergey V. Viukov, Amnon Sharir, Idit Eshkar-Oren, Randall S. Johnson, Elazar Zelzer
Journal: Development
Development (2007) 134 (21): 3917–3928.
DOI: https://doi.org/10.1242/dev.008441
Published: 1 November 2007
... limb bud mesenchyme. Developmental analysis of Hif1 α-depleted limbs revealed abnormal cartilage and joint formation in the autopod,suggesting that HIF1α is part of a mechanism that regulates the differentiation of hypoxic prechondrogenic cells. Dramatically reduced cartilage formation in Hif1 α...
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Includes: Supplementary data
Journal Articles

VEGFA is necessary for chondrocyte survival during bone development

Elazar Zelzer, Roni Mamluk, Napoleone Ferrara, Randall S. Johnson, Ernestina Schipani, Bjorn R. Olsen
Journal: Development
Development (2004) 131 (9): 2161–2171.
DOI: https://doi.org/10.1242/dev.01053
Published: 1 May 2004
... cells in the center of the hypertrophic domains express all three markers. * Author for correspondence (e-mail: bjorn_olsen@hms.harvard.edu ) 30 12 2003 © 2004. 2004 Conditional knockout mice VEGFA Chondrocyte survival Bone development Angiogenesis HIF1 HIF1α VEGF...
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Journal Articles

HIF1α is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

Tiffany N. Seagroves, Darryl Hadsell, Jim McManaman, Carol Palmer, Debbie Liao, Wayne McNulty, Bryan Welm, Kay-Uwe Wagner, Margaret Neville, Randall S. Johnson
Journal: Development
Development (2003) 130 (8): 1713–1724.
DOI: https://doi.org/10.1242/dev.00403
Published: 15 April 2003
... plays a critical role in the differentiation and function of the mammary epithelium. * Author for correspondence (e-mail: rjohnson@biomail.ucsd.edu ) 15 1 2003 © 2003. 2003 Hypoxia HIF1 Mammary gland Lactation Differentiation Metabolism Mouse In response to hypoxia...
View article titled, HIF1α is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland
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