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Keywords: HIF1
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Journal Articles
Journal: Development
Development (2007) 134 (21): 3917–3928.
Published: 1 November 2007
... limb bud mesenchyme. Developmental analysis of Hif1 α-depleted limbs revealed abnormal cartilage and joint formation in the autopod,suggesting that HIF1α is part of a mechanism that regulates the differentiation of hypoxic prechondrogenic cells. Dramatically reduced cartilage formation in Hif1 α...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 2161–2171.
Published: 1 May 2004
..., hormones and growth factors, induce stabilization of the HIF1 heterodimeric transcription complex. This complex is composed of HIF1α and HIF1β. HIF1β is constitutively expressed, whereas HIF1α is tightly regulated( Maxwell et al., 1993 ; Semenza and Wang, 1992 ; Wang and Semenza, 1993 ; Wang and Semenza...
Journal Articles