... of PCD in the embryonic ventral nerve cord (VNC). We traced the spatio-temporal pattern of PCD and compared the appearance of, and total cell numbers in,thoracic and abdominal neuromeres of wild-type and PCD-deficient H99 mutant embryos. Furthermore, we have examined the clonal origin and fate...

... or in combination must be performed. Why do caspase-inhibited embryos have extra cells? White et al.(White et al., 1994) showed that there are extra cells in the CNS of homozygous H99 embryos. Our time-lapse analysis has shown that dying neurons are generally cleared by macrophages. We and others have also...

... implicated in Drosophila apoptosis. The positive regulators, reaper (rpr), head involution defective (hid) and grim , as well as the negative regulators, DIAP1 and DIAP2 , are transcribed during oogenesis. However, germline clones homozygous for the deficiency Df(3)H99 , which deletes rpr, hid and grim...