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Keywords: H4K20me3
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Journal Articles

H4K20me3 marks distal intergenic and repetitive regions in human mature spermatozoa

Nihan Ozturk, Temuujin Dansranjavin, Sabrina Gies, Damien Calay, Shanjid Shiplu, Catherine Creppe, Jan Hendrickx, Undraga Schagdarsurengin
Journal: Development
Development (2021) 148 (15): dev196477.
https://doi.org/10.1242/dev.196477
Published: 3 August 2021
...-coding and repetitive DNA. We therefore analyzed the genome-wide distribution of the heterochromatic marker H4K20me3 in human sperm and somatic (K562) cells. To specify the function of sperm histones, we compared all H4K20me3-containing and -free loci in the sperm genome. Sperm and somatic cells...
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Includes: Supplementary data
Journal Articles

H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells

Jiji T. Kurup, Zhijun Han, Wenfei Jin, Benjamin L. Kidder
Journal: Development
Development (2020) 147 (23): dev188516.
https://doi.org/10.1242/dev.188516
Published: 4 December 2020
...Jiji T. Kurup; Zhijun Han; Wenfei Jin; Benjamin L. Kidder ABSTRACT Heterochromatin, a densely packed chromatin state that is transcriptionally silent, is a critical regulator of gene expression. However, it is unclear how the repressive histone modification H4K20me3 or the histone methyltransferase...
View article titled, <span class="search-highlight">H4K20me3</span> methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells
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Includes: Supplementary data