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Keywords: Gut
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Journal Articles
Journal: Development
Development (2021) 148 (3): dev182543.
Published: 08 February 2021
...Yi-Ning Kang; Candice Fung; Pieter Vanden Berghe ABSTRACT During embryonic development, the gut is innervated by intrinsic (enteric) and extrinsic nerves. Focusing on mammalian ENS development, in this Review we highlight how important the different compartments of this innervation are to assure...
Journal Articles
Journal: Development
Development (2017) 144 (15): 2764–2770.
Published: 01 August 2017
... it remains controversial whether AChE functions in this capacity in vivo . Here, we show that AChE plays an essential non-classical role in vertebrate gut morphogenesis. Exposure of Xenopus embryos to AChE-inhibiting chemicals results in severe defects in intestinal development. Tissue-targeted loss...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (8): 1477–1483.
Published: 15 April 2017
... rotation of the intestine is directed by forces outside the gut, but the morphogenetic events that generate anatomical asymmetry in other regions of the digestive tract remain unknown. Here, we show in mouse and Xenopus that the mechanisms that drive the curvature of the stomach are intrinsic to the gut...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (24): 4740–4750.
Published: 15 December 2014
...-6-10 Lengyel , J. A. and Iwaki , D. D. ( 2002 ). It takes guts: the Drosophila hindgut as a model system for organogenesis . Dev. Biol. 243 , 1 - 19 . 10.1006/dbio.2002.0577 Li , H. , Handsaker , B. , Wysoker , A. , Fennell , T. , Ruan , J. , Homer...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (7): 1457–1466.
Published: 01 April 2013
... role of JNK in this context has remained elusive. Here, we show that JNK activity is indispensable for the rearrangement of endoderm cells that underlies the elongation of the Xenopus gut tube. Whereas Rho kinase is necessary to induce cell intercalation and remodel adhesive contacts, we have found...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (18): 3129–3137.
Published: 15 September 2010
... of the somatic gonad, the gut and other non-gonadal tissues, as well as in sperm, but expression is not observed in oocytes. Results of tissue-specific egrh-1(RNAi) experiments and genetic mosaic analyses revealed that EGRH-1 function is necessary in the soma and, surprisingly, this function is required in both...
Journal Articles
Journal: Development
Development (2010) 137 (8): 1339–1349.
Published: 15 April 2010
... is essential for cell shape changes and morphogenesis in the developing vertebrate gut and that Shroom3 transcription in the gut requires the Pitx1 transcription factor. Moreover, we show that Pitx proteins directly activate Shroom3 transcription, and we identify Pitx-responsive regulatory elements...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (18): 3143–3152.
Published: 15 September 2009
...Cammon B. Arrington; H. Joseph Yost One of the first steps in zebrafish heart and gut organogenesis is the migration of bilateral primordia to the midline to form cardiac and gut tubes. The mechanisms that regulate this process are poorly understood. Here we show that the proteoglycan syndecan 2...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (15): 2613–2621.
Published: 01 August 2009
...) as an HSC inducing signal. * Author for correspondence (e-mail: e.dzierzak@erasmusmc.nl ) 21 5 2009 © 2009. 2009 AGM Hematopoiesis Hedgehog Gut Mouse embryo Positional information Patterning of the vertebrate embryo occurs through the complex interactions between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (9): 1681–1691.
Published: 01 May 2008
... the number of NCC by ablating the neural tube adjacent to somites 3-6 to produce aganglionic gut. We then back-transplanted various somite lengths of quail neural tube into the ablated region to determine the `tipping point',whereby sufficient progenitors were available for complete ENS formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (23): 5317–5328.
Published: 01 December 2005
... transition (EMT), and subsequently differentiate into endothelial and vascular smooth muscle cells. This is thought to be a unique process in blood vessel formation. Still,structural and developmental similarities between the heart and gut led us to test the hypothesis that a conserved or related mechanism...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (4): 763–774.
Published: 15 February 2005
..., revealed GATA5 and 6 as the most critical for the development of the gut and the liver. It has been shown that GATA factors act in a cascade in the process of endoderm formation in C. elegans ( Maduro and Rothman, 2002 ). In addition, GATA4 and 6 induce each other as well as endoderm in mouse ES cells...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3637–3647.
Published: 01 August 2004
...Hsiu-Ting Tseng; Rina Shah; Milan Jamrich Development of the visceral mesoderm is a critical process in the organogenesis of the gut. Elucidation of function and regulation of genes involved in the development of visceral mesoderm is therefore essential for an understanding of gut organogenesis...
Journal Articles
Journal: Development
Development (2002) 129 (12): 2785–2796.
Published: 15 June 2002
...Alan J. Burns; Jean-Marie M. Delalande; Nicole M. Le Douarin The enteric nervous system (ENS) is derived from vagal and sacral neural crest cells (NCC). Within the embryonic avian gut, vagal NCC migrate in a rostrocaudal direction to form the majority of neurons and glia along the entire length...
Journal Articles
Journal: Development
Development (2002) 129 (3): 551–561.
Published: 01 February 2002
... malformations occur. The phenotype is specific to HFGa13 expression in the posterior endoderm, and includes taillessness and severe gut/genitourinary (GGU) malformations. Finally, we show that chick HFGa13 negatively regulates expression of Hoxd13 and antagonizes functions of both endogenous Hoxa13 and Hoxd13...
Journal Articles
Journal: Development
Development (1985) 85 (1): 191–206.
Published: 01 February 1985
...), and there is also evidence that lipoproteins are synthesized much earlier, at 29 days postfertilization (Gitlin & Biasucci, 1969). We Major key words: Apolipoproteins, human, embryo, yolk sack. Minor key words: Gut, stomach, liver, trophoblast, brain, transferrin, alphafoetoprotein. 192 W-K. SHI AND OTHERS have...