... react with repulsive turning or growth cone collapse when confronted with ephrin-A5-Fc bound to beads. However, when added in soluble form to the medium, ephrin-A5 induces growth cone collapse, comparable to data from chick. The analysis of growth cone behaviour in a gradient of soluble ephrin-A5...

... cone forms at the dorsal tip of the predominating finger. Thus, we observe that complete growth cone collapse occurs in vivo and not just in culture assays. In contrast to studies indicating that collapse occurs upon contact with repulsive substrata, collapse of the VD growth cones may result from...

... collapsin-1 semaphorin-D semaphorin-III spinal cord sensory afferent trk-C antibody repulsion repellent growth cone collapse guidance pathfinding chick The correct wiring together of the nervous system requires that specific axonal growth cones respond appropriately to a variety...

...: Physiology Department, University of Edinburgh, Medical School, Teviot Place, Edinburgh † Author for correspondence © 1991 by Company of Biologists 1991 retinotectal glial cells growth cone collapse in vitro Xenopus laevis During the development of the visual system...