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Keywords: Growth
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Journal Articles
Journal: Development
Development (2021) 148 (8): dev197087.
Published: 23 April 2021
... activation of p38 through Ser83, and that the phosphorylation of p38 during regeneration is nutrient sensitive. This mechanism is important for discriminating between p38 and JNK in the cells involved in tissue repair and regenerative growth. From our results, we concluded that Ser83 of the Ask1 YH_GVRE S...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev196063.
Published: 11 January 2021
...Laura Boulan; Pierre Léopold ABSTRACT The sizes of living organisms span over 20 orders of magnitude or so. This daunting observation could intimidate researchers aiming to understand the general mechanisms controlling growth. However, recent progress suggests the existence of principles common to...
Journal Articles
Journal: Development
Development (2020) 147 (17): dev177956.
Published: 11 September 2020
...Caitlin McQueen; Matthew Towers ABSTRACT The vertebrate limb continues to serve as an influential model of growth, morphogenesis and pattern formation. With this Review, we aim to give an up-to-date picture of how a population of undifferentiated cells develops into the complex pattern of the limb...
Journal Articles
Journal: Development
Development (2020) 147 (7): dev184044.
Published: 08 April 2020
... bls2 , bls3 and bls5 subfamilies. In the case of the second RNA sequence, inhibition of all members of the transcribed families was demonstrated by qPCR analysis ( Figs S3B,C, S5B, S6B ) In long-term growth experiments involving RNAi, animals were fed twice per week: food was provided in the...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2019) 146 (20): dev174409.
Published: 17 October 2019
... SCFR correlates with glia differentiation of late retinal progenitor cells (RPCs), retinal vasculogenesis and homeostasis of the blood-retinal barrier. However, the role of SCF/SCFR signaling in the growth and development of the neural retina (NR), especially in the early embryonic stage, remains...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (18): dev167106.
Published: 16 September 2019
...John Robert Davis; Nicolas Tapon ABSTRACT The Hippo signalling pathway and its transcriptional co-activator targets Yorkie/YAP/TAZ first came to attention because of their role in tissue growth control. Over the past 15 years, it has become clear that, like other developmental pathways (e.g. the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (5): dev151894.
Published: 14 March 2019
...Ainoa Planas-Riverola; Aditi Gupta; Isabel Betegón-Putze; Nadja Bosch; Marta Ibañes; Ana I. Caño-Delgado ABSTRACT Brassinosteroids (BRs) are steroid hormones that are essential for plant growth and development. These hormones control the division, elongation and differentiation of various cell...
Journal Articles
Journal: Development
Development (2018) 145 (21): dev165654.
Published: 02 November 2018
...Kurt Buhler; Jason Clements; Mattias Winant; Lenz Bolckmans; Veerle Vulsteke; Patrick Callaerts ABSTRACT Growth and maturation are coordinated processes in all animals. Integration of internal cues, such as signalling pathways, with external cues, such as nutritional status, is paramount for an...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (11): dev161356.
Published: 11 June 2018
...Sarah D. Neuman; Arash Bashirullah ABSTRACT All animals must coordinate growth rate and timing of maturation to reach the appropriate final size. Here, we describe hobbit , a novel and conserved gene identified in a forward genetic screen for Drosophila animals with small body size. hobbit is...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (6): dev160101.
Published: 19 March 2018
...H. Frederik Nijhout; Emily Laub; Laura W. Grunert ABSTRACT The wing imaginal disks of Lepidoptera can be grown in tissue culture, but require both insulin and ecdysone to grow normally. Here, we investigate the contributions the two hormones make to growth. Ecdysone is required to maintain mitoses...
Journal Articles
Journal: Development
Development (2018) 145 (2): dev146829.
Published: 25 January 2018
... + progenitors, in a mechanism reminiscent of ductal organ development and thyroid evolution from an exocrine forerunner. Thyroid Progenitor Fgf10 Sox9 Mouse Growth Differentiation Mouse thyroid morphogenesis recapitulates in less than one week the developmental program of the human thyroid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4238–4248.
Published: 01 December 2017
...Kenneth D. Irvine; Boris I. Shraiman In his classic book On Growth and Form , D'Arcy Thompson discussed the necessity of a physical and mathematical approach to understanding the relationship between growth and form. The past century has seen extraordinary advances in our understanding of...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2381–2391.
Published: 01 July 2017
... the physical mechanisms of heart tube and foregut formation. According to our hypothesis, differential anisotropic growth between mesoderm and endoderm drives diagonal folding. Then, active contraction along the anterior intestinal portal generates tension to elongate the foregut and heart tube. We...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (19): 3623–3631.
Published: 01 October 2016
... in the developing limbs and their function is required for limb growth in both insects and chordates. Despite the fundamental and conserved role that these transcription factors play during appendage development, their target genes and the mechanisms by which they participate in control limb growth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (11): 2339–2348.
Published: 01 June 2014
...Idse Heemskerk; Thomas Lecuit; Loïc LeGoff In the course of morphogenesis, tissues change shape and grow. How this is orchestrated is largely unknown, partly owing to the lack of experimental methods to visualize and quantify growth. Here, we describe a novel experimental approach to investigate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2150–2156.
Published: 15 May 2014
...Inna Averbukh; Danny Ben-Zvi; Siddhartha Mishra; Naama Barkai Morphogen gradients guide the patterning of tissues and organs during the development of multicellular organisms. In many cases, morphogen signaling is also required for tissue growth. The consequences of this interplay between growth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (9): 1884–1893.
Published: 01 May 2014
...Ortrud Wartlick; Frank Jülicher; Marcos Gonzalez-Gaitan During morphogenesis, organs grow to stereotyped sizes, but growth control mechanisms are poorly understood. Here, we measured the signaling dynamics of the morphogen Dpp, one of several Drosophila factors controlling morphogenetic growth, in...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (24): 4926–4936.
Published: 15 December 2013
...) transcriptome profiling for each null strain, we show that the different CHDs regulate distinct gene sets during both growth and development. ChdC is an apparent ortholog of the mammalian Class III CHD group that is associated with the human CHARGE syndrome, and GO analyses of aberrant gene expression in chdC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4776–4787.
Published: 01 December 2013
...Ling Li; Sarah Anderson; Julie Secombe; Robert N. Eisenman The essential and highly conserved role of Myc in organismal growth and development is dependent on the control of Myc protein abundance. It is now well established that Myc levels are in part regulated by ubiquitin-dependent proteasomal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (17): 3601–3612.
Published: 01 September 2013
...Christopher M. Webster; Lianfeng Wu; Denzil Douglas; Alexander A. Soukas The target of rapamycin complex 2 (TORC2) pathway is evolutionarily conserved and regulates cellular energetics, growth and metabolism. Loss of function of the essential TORC2 subunit Rictor (RICT-1) in Caenorhabditis elegans...
Includes: Supplementary data