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Keywords: Gremlin
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Journal Articles
Journal: Development
Development (2014) 141 (9): 1906–1914.
Published: 1 May 2014
... 3 3 2014 © 2014. Published by The Company of Biologists Ltd 2014 Enhancer Gli Gremlin Limb development Silencer Sonic Hedgehog Mouse The Hedgehog (Hh) pathway is one of the primary signaling mechanisms underlying developmental patterning in organisms ranging from...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (3): 465–474.
Published: 1 February 2011
.... Conversely, Tbx2 loss of function expands the boundary of each component of the pronephric nephron, resulting in an enlarged pronephros. BMP signals induce Tbx2 in the non-nephric mesoderm, which inhibits the expression of the nephric markers Hey1 and Gremlin . Importantly, these pronephric molecules repress...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (15): 3795–3804.
Published: 1 August 2004
... of mesodermal-epithelial signals mediated in part by Gremlin (a modulator of the BMP pathway). Our results suggest that SOX9 is necessary and sufficient to specify the pyloric sphincter epithelial properties. † Author for correspondence (e-mail: desanta@igh.cnrs.fr ) * These authors contributed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (14): 3401–3410.
Published: 15 July 2004
... that the BMP antagonist gremlin ( Grem1 ) is essential to initiate these epithelial-mesenchymal signaling interactions during limb and metanephric kidney organogenesis. A Grem1 null mutation in the mouse generated by gene targeting causes neonatal lethality because of the lack of kidneys and lung septation...