... during metamorphosis. However, the important role of endoplasmic reticulum (ER)-to-Golgi transport in dendrite pruning remains unknown. Here, in a clonal screen, we have identified Yif1, an uncharacterized Drosophila homolog of Yif1p that is known to be a regulator of ER-to-Golgi transport in yeast. We...

... genetic linkage mapping and whole-exome sequencing, we identified a loss-of-function mutation in the Golgb1 gene that co-segregated with cleft palate in a new mutant mouse line. Golgb1 is a ubiquitously expressed large coiled-coil protein, also known as giantin, that is localized at the Golgi membrane...

... glycosylation are unknown. A genetic screen for relevant mutations in Drosophila generated the sugar-free frosting ( sff ) mutant that reveals a new function for protein kinases in regulating substrate flux through specific Golgi processing pathways. Sff is the Drosophila homolog of SAD kinase, which regulates...

... endomembrane markers revealed that NEV localizes to the trans - Golgi network and endosomes in Arabidopsis root epidermal cells. Interestingly, transmission electron micrographs of abscission zone regions from wild-type and nev flowers reveal defects in the structure of the Golgi apparatus and extensive...

... to the endoplasmic reticulum. Strikingly, coexpression of the dorsal group gene windbeutel in those cells directs Pipe to the Golgi. Similarly, Pipe protein exhibits an altered subcellular localization in the follicle cells of females mutant for windbeutel . Thus, Windbeutel protein enables the correct subcellular...

... Mauthner Rohon-Beard trigeminal Golgi HNK-1. How do developing neurons acquire their specific morphologies, grow their axons along specific pathways and recognize specific target cells? Evidence is accumulating that interactions that specify cell type (Knust and Campos-Ortega, 1989), as well...

... and acidic vesicle fraction (100kD antigen), Golgi apparatus (135kD antigen) and coated vesicles (clathrin). The distribution of these antigens has also been examined in isolated 8-cell and 16-cell-stage blastomeres of various ages and phenotypes. Endoplasmic reticulum is detected only weakly in the oocyte...