... metabolism and cell growth. Silencing of these genes impaired early glia proliferation and subsequent differentiation. Dref controls proliferation via activation of the Pdm3 transcription factor, whereas glial differentiation is regulated via Dref and the homeodomain protein Cut. Cut expression is controlled...

... subsequent glial differentiation. In order to better understand glial cell differentiation, we have screened for genes whose expression in glial cells depends on the activity of POINTED. Using an enhancer trap approach, we have identified loco as such a gene. loco is expressed in most lateral CNS glial cells...

.... These findings challenge the common view on the establishment of cell diversity in the nervous system. Strikingly, ectopic glide/gcm overrides positional information by repressing the endogenous developmental program. These findings also indicate that glial differentiation tightly depends on glide/gcm...

... and differentiation along the same path-ways that are formed during the preceding phases of neuronal migration. 07 10 1992 © 1993 by Company of Biologists 1993 enteric nervous system glial progenitor Manduca sexta glial differentiation cell lineage A key feature in the formation...

... glial differentiation myelination The neural epithelium yields, besides neurons, cells that are closely associated with axons, which ensheath them and produce myelin, a structure that increases efficiency of nerve impulse conduction. These cells are Schwann cells in the peripheral nervous...