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Keywords: Germline stem cells
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Journal Articles
Journal: Development
Development (2022) 149 (3): dev199890.
Published: 4 February 2022
... represent mean±s.d. (see Table S2 ). The fact that we observe brk expression in cells that comprise the germline stem cell niche (i.e. TF, CCs and ECs) suggests that Brk plays a role in regulating germline homeostasis. To test this, we generated deletions of the PPE and its distal and proximal...
Includes: Supplementary data
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Journal: Development
Development (2021) 148 (7): dev187773.
Published: 15 April 2021
...Sylvain Bertho; Mara Clapp; Torsten U. Banisch; Jan Bandemer; Erez Raz; Florence L. Marlow ABSTRACT Fertility and gamete reserves are maintained by asymmetric divisions of the germline stem cells to produce new stem cells or daughters that differentiate as gametes. Before entering meiosis...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2019) 146 (2): dev167643.
Published: 29 January 2019
... Niche Germline stem cells Somatic stem cells Testis Intestine Intestinal stem cells Enterocytes Wing disc Cytokines Proliferation Survival Differentiation Cell competition Niche competition Inflammation Regeneration Cellular plasticity Cell reprogramming In the early 1990s...
Journal Articles
Journal: Development
Development (2018) 145 (17): dev161786.
Published: 7 September 2018
... and developmental functions of piRNAs. Drosophila embryonic patterning Germ cells Germline stem cells Maternal mRNAs Metabolism Mouse spermatogenesis mRNA localization mRNA stability piRNAs PIWI proteins Regeneration Stem cells Piwi-interacting RNAs (piRNAs) are a class of small 21-32...
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Journal Articles
Journal: Development
Development (2017) 144 (18): 3224–3231.
Published: 15 September 2017
...Lichao Luo; Chia Keng Siah; Yu Cai Homeostasis of adult tissues is maintained by a small number of stem cells, which are sustained by their niches. In the Drosophila female germline stem cell (GSC) niche, Decapentaplegic (Dpp) is the primary factor that promotes GSC self-renewal. However...
Includes: Supplementary data
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Journal: Development
Development (2015) 142 (5): 883–892.
Published: 1 March 2015
... , somatic precursors for niches, and germ cells that will become germline stem cells, co-develop. Somatic precursors proliferate during the first 3 days of larval development. By mid-third instar, adult terminal filament (TF) (part of the germline stem cell niche) cells first appear, and differentiation...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (2): 259–268.
Published: 15 January 2014
... fully rescues the Zfrp8 phenotype, underlining the functional conservation of Zfrp8/PDCD2. The piRNA pathway is essential in early oogenesis, and we find that nuclear localization of Zfrp8 in germline stem cells and their offspring is regulated by some piRNA pathway genes. We also show that Zfrp8 forms...
Includes: Supplementary data
Journal Articles
Journal Articles
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Journal Articles