... declare no competing or financial interests. 18 7 2023 2 10 2023 © 2023. Published by The Company of Biologists Ltd 2023 Highlighted Article: A mathematical model for growing networks by oscillations on nodes reproduces germline cyst topologies in invertebrates...

...Vineet Kumar; Yaniv M. Elkouby ABSTRACT Oocytes develop in the germline cyst, a cellular organization in which germ cells are tightly interconnected and surrounded by somatic cells. The cyst produces oocytes for follicle formation and is a hub for essential processes in meiosis and oocyte...

... of dazl mutants revealed the essential role of Dazl in regulating incomplete cytokinesis, germline cyst formation and germline stem cell specification before the meiotic transition. Accordingly, dazl mutant GCs form defective ring canals, and ultimately remain as individual cells that fail...

... on a process of germline cyst breakdown during the perinatal period. The mechanisms regulating this process are poorly understood. Here we demonstrate that c-Jun amino-terminal kinase (JNK) signaling is crucial for germline cyst breakdown and primordial follicle formation. JNK was specifically localized...