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Keywords: Genetics
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Journal Articles
Journal: Development
Development (2023) 150 (4): dev201313.
Published: 13 February 2023
...Alexis Garretson; Beth L. Dumont; Mary Ann Handel ABSTRACT Genetic analyses of mammalian gametogenesis and fertility have the potential to inform about two important and interrelated clinical areas: infertility and contraception. Here, we address the genetics and genomics underlying gamete...
Journal Articles
Journal: Development
Development (2019) 146 (14): dev177261.
Published: 19 July 2019
... and the use of synthetic systems to test models. This highly dynamic, interdisciplinary mix of quantitative developmental genetics, bioengineering, synthetic biology and artificial life aimed to reveal how evolution exploits physical forces and genetics to implement the cell- and tissue-level decision-making...
Journal Articles
Journal: Development
Development (2018) 145 (20): dev164384.
Published: 22 October 2018
... mammalian development and emphasizes their pleiotropic role in cell lineage decisions and early organogenesis. GATA factors Gene redundancy Genetics Lineage specification Mouse development Transcription Human diseases During vertebrate development, the GATA family of transcription...
Journal Articles
Journal: Development
Development (2018) 145 (1): dev151944.
Published: 3 January 2018
... leaflet maturation remains poorly understood. Here, we show in mouse that neural crest cells from pre-otic and post-otic regions make distinct contributions to the arterial valve leaflets. Genetic fate-mapping analysis of Krox20-expressing neural crest cells shows a large contribution to the borders...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1743–1763.
Published: 15 May 2017
... highlight additional Notch receptors or ligands that are likely to be involved in human genetic diseases. * Author for correspondence ( emma.andersson@ki.se ) Competing interests The authors declare no competing or financial interests. © 2017. Published by The Company of Biologists Ltd...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (21): 3994–4002.
Published: 1 November 2016
... showed reduced expression of multiple neuroretina-expressed FGFs and canonical FGF-regulated genes in neuroretina. When FGF expression was genetically restored in Lhx2 -deficient neuroretina of Chx10-Cre;Lhx2 lox/lox mice, we observed a partial but nonetheless substantial rescue of the defects in lens...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 1105–1116.
Published: 1 March 2005
...: University of Virginia Health Systems, Department of Pathlogy, 415 Lane Road, Charlottesville, VA 22908, USA 29 12 2004 ©2005. 2005 Epiboly Radial intercalation E-cadherin Epiblast Teleost Morphogenesis Genetics Antisense Zebrafish Here we report on the molecular identity...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (16): 3907–3920.
Published: 15 August 2004
... ribosomal protein mutation. * Author for correspondence (e-mail: tglaser@umich.edu ) 12 5 2004 ©2004. 2004 Mouse Genetics Minute Ribosome Cell cycle Retina Bst The Minutes are an intriguing group of eukaryotic mutations that have been valuable in elucidating...
Journal Articles
Journal: Development
Development (2003) 130 (17): 3917–3928.
Published: 1 September 2003
... understood. To identify genes required for the formation of vertebrate digestive organs we performed a genetic screen in zebrafish. We isolated the nil per os ( npo ) mutation,which arrests morphogenesis and cytodifferentiation of the gut and exocrine pancreas in a primodial state. We identified the npo gene...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 115 (2): 449–462.
Published: 1 June 1992
... of the antennal and eye structures (See Fig. 5 ). Genetic analysis of the developing fly has identified a growing class of genes that function in the development of multiple tissues. One such gene is Notch , which plays important roles in cell fate decisions in the embryonic neuroectoderm as well...
Journal Articles
Journal Articles
Journal: Development
Development (1991) 113 (Supplement_2): 47–57.
Published: 1 April 1991
... the neurons and their axonal paths occur at close range and involve multiple, possibly combinatorial, transmitterindependent pathways. Copyright © 1991 by Company of Biologists 1991 genetics mutation zebrafish primary neuron notoneuron somite muscle notochord floor plate cell nteractions...
Journal Articles
Journal: Development
Development (1990) 110 (2): 471–475.
Published: 1 October 1990
...Dorothy C. Bennett; Dennis Huszar; Philip J. Laipis; Rudolf Jaenisch; Ian J. Jackson ABSTRACT A mouse cDNA for the developmentally controlled, melanocyte-specific protein, tyrosinase-related protein 1 (TRP-1), was previously cloned and reported to show genetic linkage with the coat-colour locus...
Journal Articles
Journal: Development
Development (1990) 108 (1): 107–119.
Published: 1 January 1990
... of a cell and that there must be another developmental clock that activates the determinative inventory for the early decision-making. * Present address 17 10 1989 © 1990 by Company of Biologists 1990 C. elegans genetics stem cell determination developmental clock...
Journal Articles
Journal: Development
Development (1987) 100 (3): 365–382.
Published: 1 July 1987
... the body wall. 24 03 1987 © 1987 by Company of Biologists 1987 Caenorhabditis elegans neurone migration genetics cell lineage axon Cells assemble into organs by selectively attaching to neighbouring cells. In animals, the final neighbours need not be close relatives...