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Keywords: Genetics
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Journal Articles
In collection:
Advocacy
Journal: Development
Development (2023) 150 (4): dev201313.
Published: 13 February 2023
...Alexis Garretson; Beth L. Dumont; Mary Ann Handel ABSTRACT Genetic analyses of mammalian gametogenesis and fertility have the potential to inform about two important and interrelated clinical areas: infertility and contraception. Here, we address the genetics and genomics underlying gamete...
Journal Articles
Journal: Development
Development (2019) 146 (14): dev177261.
Published: 19 July 2019
... and the use of synthetic systems to test models. This highly dynamic, interdisciplinary mix of quantitative developmental genetics, bioengineering, synthetic biology and artificial life aimed to reveal how evolution exploits physical forces and genetics to implement the cell- and tissue-level decision-making...
Journal Articles
Journal: Development
Development (2018) 145 (20): dev164384.
Published: 22 October 2018
... mammalian development and emphasizes their pleiotropic role in cell lineage decisions and early organogenesis. GATA factors Gene redundancy Genetics Lineage specification Mouse development Transcription Human diseases Canadian Institutes of Health Research 10.13039/501100000024 MOP...
Journal Articles
Journal: Development
Development (2018) 145 (1): dev151944.
Published: 3 January 2018
... leaflet maturation remains poorly understood. Here, we show in mouse that neural crest cells from pre-otic and post-otic regions make distinct contributions to the arterial valve leaflets. Genetic fate-mapping analysis of Krox20-expressing neural crest cells shows a large contribution to the borders...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1743–1763.
Published: 15 May 2017
... highlight additional Notch receptors or ligands that are likely to be involved in human genetic diseases. * Author for correspondence ([email protected]) Competing interests The authors declare no competing or financial interests. © 2017. Published by The Company of Biologists Ltd 2017...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (21): 3994–4002.
Published: 1 November 2016
... showed reduced expression of multiple neuroretina-expressed FGFs and canonical FGF-regulated genes in neuroretina. When FGF expression was genetically restored in Lhx2 -deficient neuroretina of Chx10-Cre;Lhx2 lox/lox mice, we observed a partial but nonetheless substantial rescue of the defects in lens...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 1105–1116.
Published: 1 March 2005
... of linkage group I. Genetics 139 , 1727 -1735. Kane, D. and Adams, R. (2002). Life at the edge: epiboly and involution in the zebrafish. In Gastrulation Movements. Vol. 40 (ed. L. Solnica-Krezel), pp. 117 -135. Heidelberg:Springer-Verlag. Kane, D. A. and Kimmel, C. B. (1993). The zebrafish...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (16): 3907–3920.
Published: 15 August 2004
... ribosomal protein mutation. * Author for correspondence (e-mail: [email protected]) 12 5 2004 ©2004. 2004 Mouse Genetics Minute Ribosome Cell cycle Retina Bst The Minutes are an intriguing group of eukaryotic mutations that have been valuable in elucidating...
Journal Articles
Journal: Development
Development (2003) 130 (17): 3917–3928.
Published: 1 September 2003
... understood. To identify genes required for the formation of vertebrate digestive organs we performed a genetic screen in zebrafish. We isolated the nil per os (npo) mutation,which arrests morphogenesis and cytodifferentiation of the gut and exocrine pancreas in a primodial state. We identified the npo gene...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 115 (2): 449–462.
Published: 1 June 1992
... receptor retinoid X receptor oogenesis eye morphogenesis genetics 9-cis- retinoic acid The actions of the steroid, thyroid and retinoid hormones are predominantly mediated by the members of the steroid receptor superfamily. These receptors are ligand-dependent transcription factors that alter...
Journal Articles
Journal Articles
Journal: Development
Development (1991) 113 (Supplement_2): 47–57.
Published: 1 April 1991
... the neurons and their axonal paths occur at close range and involve multiple, possibly combinatorial, transmitterindependent pathways. Copyright © 1991 by Company of Biologists 1991 genetics mutation zebrafish primary neuron notoneuron somite muscle notochord floor plate cell nteractions...
Journal Articles
Journal: Development
Development (1990) 110 (2): 471–475.
Published: 1 October 1990
...Dorothy C. Bennett; Dennis Huszar; Philip J. Laipis; Rudolf Jaenisch; Ian J. Jackson ABSTRACT A mouse cDNA for the developmentally controlled, melanocyte-specific protein, tyrosinase-related protein 1 (TRP-1), was previously cloned and reported to show genetic linkage with the coat-colour locus...
Journal Articles
Journal: Development
Development (1990) 108 (1): 107–119.
Published: 1 January 1990
.... (1985). Plasticity of the differential state . Science 230 , 758 – 766 . 10.1126/science.2414846 Brenner , S. (1974). The genetics of C. elegans. Genetics 77 , 71 – 94 . Cowan , A. E. and McIntosh , J. R. (1985). Mapping the distribution of differentiation...
Journal Articles
Journal: Development
Development (1987) 100 (3): 365–382.
Published: 1 July 1987
... the body wall. 24 03 1987 © 1987 by Company of Biologists 1987 Caenorhabditis elegans neurone migration genetics cell lineage axon Cells assemble into organs by selectively attaching to neighbouring cells. In animals, the final neighbours need not be close relatives...