... neovascularization and cardiomyocyte survival. Additionally, we found that inhibition of one type of cell proliferation (namely, hepatocytes) induces the lineage conversion of another type cells (i.e. ductal cells) during tissue regeneration. These results validate the use of ip21-GFP mice as a new genetic tool...

... methods Genetic tools Most vertebrate tissues undergo continuous cell turnover to maintain tissue homeostasis, and cells that no longer exert their function correctly are eliminated and replaced by new ones. This continuous cellular turnover is not homogenous in all tissues: whereas gut...