... but a small medial domain in the fourth ventricle roof plate is derived from cells that have either expressed gdf7 or are derived from gdf7 -positive precursors ( Hunter and Dymecki, 2007 ). However, although, by inference, this establishes the spatial dynamics of cells that contribute fourth ventricle...

...-mail: [email protected] ) * Present address: Department of Anatomy and Developmental Biology, UCL,Gower Street, London, WC1E 6BT, UK 25 5 2006 © 2006. 2006 Isthmic organizer Mid/hindbrain organizer Roof plate FGF8 Follistatin Activin BMP7 GDF7 Chick Quail The roof...

...), diencephalon (3rd ventricle) and dorsomedial telencephalon bilaterally (lateral ventricles). All of these sites lie at or near the embryonic dorsal midline (DM), which acts as a CNS patterning center. We therefore examined DM-CP relationships using normal and Gdf7 (Bmp12)transgenic embryos to fate map...