1-7 of 7
Keywords: Gastruloid
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal Articles
Journal: Development
Development (2023) 150 (17): dev201790.
Published: 11 September 2023
... to signalling cocktails and aggregated into large embryonic bodies, but these do not recapitulate the native embryonic environment during PGC formation. Here, we show that mouse gastruloids, a three-dimensional in vitro model of gastrulation, contain a population of gastruloid-derived PGCLCs (Gld-PGCLCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (16): dev201663.
Published: 17 August 2023
...Evan J. Underhill; Jared E. Toettcher ABSTRACT Many developmental processes rely on the localized activation of receptor tyrosine kinases and their canonical downstream effectors Erk and Akt, yet the specific roles played by each of these signals is still poorly understood. Gastruloids, 3D cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (20): dev201015.
Published: 18 October 2022
... embryogenesis, and discuss their applications and findings. Blastoid Embryogenesis Embryoid Gastruloid Organogenesis Stem cell Michigan-Cambridge Research Initiative National Institutes of Health http://dx.doi.org/10.13039/100000002 R21 NS113518 R21 HD100931 R21 HD105126...
Journal Articles
Journal: Development
Development (2022) 149 (20): dev200933.
Published: 22 September 2022
... of blastocyst-like structures we refer the reader to Terhune et al. (2022) . Other stage-specific in vitro models can also represent crucial developmental processes that follow implantation. Gastruloids, for example, replicate multiple important aspects of gastrulation, the process that specifies...
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (17): dev179564.
Published: 12 September 2019
...Iain Martyn; Eric D. Siggia; Ali H. Brivanlou ABSTRACT Although fate maps of early embryos exist for nearly all model organisms, a fate map of the gastrulating human embryo remains elusive. Here, we use human gastruloids to piece together a rudimentary fate map for the human primitive streak (PS...
Includes: Supplementary data