... progenitor cells. Sin3a Foregut endoderm G1 arrest p21/Cdkn1a Progenitor cell fate Epithelial-mesenchymal signaling Mouse California Institute of Regenerative Medicine 10.13039/100007557 LA1-06915 National Institutes of Health 10.13039/100000002 LRRC-UO1HL111018...

...-II arrest. However, the mouse meta-II arrest challenges this requirement, and no downstream effector has been identified in the starfish G1 arrest. To investigate the downstream effector of MAPK in the starfish G1 arrest, we used a neutralizing antibody against Rsk and a constitutively active form...

..., indicating that no S phase occurs. The DNA content in cells sorted by fluorescent tissue-specific reporters indicates that prespore cells divide before prestalk cells and later encapsulate as G1-arrested spores. Consistent with this, germinating spores have one copy of their chromosomes, as judged...

... p27 Cell proliferation prospero G1 arrest Drosophila Unrestrained cell proliferation results in an exponential increase of cell numbers. An accurate regulation of cell proliferation is therefore required in particular in multicellular organisms where tissue-specific limits for cell...