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Keywords: Fucci imaging
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Journal Articles
Visualizing developmentally programmed endoreplication in mammals using ubiquitin oscillators
Open AccessAsako Sakaue-Sawano, Tetsushi Hoshida, Masahiro Yo, Reiko Takahashi, Kenji Ohtawa, Takashi Arai, Eiki Takahashi, Shinichi Noda, Hiroyuki Miyoshi, Atsushi Miyawaki
Journal:
Development
Development (2013) 140 (22): 4624–4632.
Published: 15 November 2013
.... In this study, we used transgenic mice expressing Fucci fluorescent cell-cycle probes that report the activity of APC Cdh1 and SCF Skp2 . By performing long-term, high temporal-resolution Fucci imaging, we were able to visualize reciprocal activation of APC Cdh1 and SCF Skp2 in differentiating TGCs and MKCs...
Includes: Supplementary data
