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Keywords: Frs3
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Journal Articles
Journal: Development
Development (2006) 133 (4): 663–673.
Published: 15 February 2006
... (Frs2, Frs3) as the principal mediators of Fgfr1 signal transduction to the MAPK and PI3K pathways. To determine the developmental requirements for Fgfr1-Frs signaling, we generated mice ( Fgfr1 Δ Frs /Δ Frs ) in which the Frs2/3-binding site on Fgfr1 is deleted. Fgfr1 Δ Frs /Δ Frs embryos die during...
Includes: Supplementary data