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Keywords: Frontonasal hypoplasiaClose
Ran Gu, Shuwen Zhang, Subbroto Kumar Saha, Yu Ji, Kurt Reynolds, Moira McMahon, Bo Sun, Mohammad Islam, Paul A. Trainor, YiPing Chen, Ying Xu, Yang Chai, Diana Burkart-Waco, Chengji J. Zhou
Development (2022) 149 (14): dev200533.
Published: 22 July 2022
... that downregulation of Msx1/Msx2 and Pax3/Pax7 as well as Pdgfra in the dorsal nasal prominences is a primary contributor, at the molecular level, to the frontonasal hypoplasia and midline facial clefts in Wls-deficient mutants. Other than the aforementioned Msx and Pax transcription factors, platelet...
Includes: Supplementary data