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Keywords: Forkhead
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Journal Articles
Journal: Development
Development (2018) 145 (12): dev165498.
Published: 26 June 2018
... these cell types remains a mystery. We find that modular expression of Forkhead domain transcription factors (Fox proteins) in the zebrafish face arises through integration of Hh, Fgf, Bmp, Edn1 and Jagged-Notch pathways. Whereas loss of C-class Fox proteins results in reduced upper facial cartilages...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (24): 4558–4570.
Published: 15 December 2016
...Maria L. Golson; Klaus H. Kaestner Forkhead box (Fox) transcription factors are evolutionarily conserved in organisms ranging from yeast to humans. They regulate diverse biological processes both during development and throughout adult life. Mutations in many Fox genes are associated with human...
Journal Articles
Journal: Development
Development (2012) 139 (14): 2625–2634.
Published: 15 July 2012
... Center, Tel Hashomer 52621, Israel ‡ Author for correspondence ( sang@nimr.mrc.ac.uk ) Competing interests statement The authors declare no competing financial interests. 28 4 2012 © 2012. 2012 Dopaminergic neuron specification Foxa2 Forkhead Chromatin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (20): 3753–3761.
Published: 15 October 2007
... particular Bmp4, are crucial for vascular tube formation, that Bmp4 expression in extraembryonic tissues requires the forkhead transcription factor Foxf1 and that the role of hedgehog proteins in this process is to activate Foxf1 expression in the mesoderm. We show in the allantois that genetic disruption of...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3297–3305.
Published: 15 September 2007
... migration. Because a dominant-negative form of FoxF inhibits Ets:VP16-induced cell migration, we asked whether FoxF activity would be sufficient for the heart cells to migrate in the absence of Ets1/2 activity. To this aim, we engineered a constitutive activator form of FoxF, by fusing its forkhead...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (24): 4827–4838.
Published: 15 December 2006
... correspondence (e-mail: kesslerd@mail.med.upenn.edu ) * Present address: Center for Stem Cell Biology, Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA 28 9 2006 © 2006. 2006 Xenopus FoxD3 Forkhead Nodal Mesoderm Transcription...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4173–4181.
Published: 01 November 2006
... skeletogenic and oral ectoderm gene regulatory networks. Dev. Biol. 261 , 55 -81. Ang, S. L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S.,Rossant, J. and Zaret, K. S. ( 1993 ). The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins...
Journal Articles
Journal: Development
Development (2006) 133 (5): 833–843.
Published: 01 March 2006
... control epithelial proliferation and survival, which account for the importance of the stroma in colon carcinoma progression. Here, we show that targeting murine Foxf1 and Foxf2 , encoding forkhead transcription factors, has pleiotropic effects on intestinal paracrine signaling. Inactivation of both Foxf2...
Journal Articles
Journal: Development
Development (2005) 132 (15): 3405–3417.
Published: 01 August 2005
... embryos is dependent upon highly conserved Forkhead and GATA transcription factor binding sites, which are bound by FOXF1 and GATA4, respectively. Furthermore, the activity of the Gata4 lateral mesoderm enhancer is attenuated by the BMP antagonist Noggin, and the enhancer is not activated in Bmp4 -null...
Journal Articles
Journal: Development
Development (2005) 132 (2): 371–382.
Published: 15 January 2005
...@mail.bio.tamu.edu ) * These authors contributed equally to this work 17 11 2004 ©2005. 2005 Preplacodal domain Otic placode Genetic network Paired Fibroblast growth factor forkhead distal-less msxC Pax proteins are key regulators of developmental processes including...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3637–3647.
Published: 01 August 2004
... tool, which can be used to specifically alter gene expression in the lateral plate mesoderm. BMP4 FoxF1 Forkhead Gut Lateral plate mesoderm Morpholino Visceral mesoderm Development of the gut requires a coordinated proliferation and differentiation of the visceral mesoderm and gut...
Journal Articles
Journal: Development
Development (2004) 131 (6): 1425–1436.
Published: 15 March 2004
.... We focus on the control of sexual dimorphism in the C. elegans gonad. We find that the forkhead transcription factor FKH-6 promotes male gonadal cell fates in XO animals. Loss-of-function fkh-6 mutant males have feminized gonads and often develop a vulva. In these mutant males, sex-specific cell...
Journal Articles
Journal: Development
Development (2004) 131 (4): 953–964.
Published: 15 February 2004
... (TTF-1), GATA-6, and forkhead transcription factors FOXA1, FOXA2, FOXF1 and FOXJ1( Cardoso, 1995 ; Costa et al., 2001 ; Perl and Whitsett, 1999 ). FOXA2 (previously termed HNF-3β) is a member of the winged helix nuclear factor gene family. In mice, Foxa2 is expressed first in the primitive streak...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (4): 933–942.
Published: 15 February 2004
... , a winged-helix/forkhead domain transcription factor. Although it has been shown that FOXL2 is expressed in adult ovaries, its function during folliculogenesis is not known. Here, we show that the murine Foxl2 gene is essential for granulosa cell differentiation and ovary maintenance. In Foxl2 lacZ...
Journal Articles
Journal: Development
Development (2003) 130 (9): 2013–2025.
Published: 01 May 2003
...Malin Hulander; Amy E. Kiernan; Sandra Rodrigo Blomqvist; Peter Carlsson; Emma-Johanna Samuelsson; Bengt R. Johansson; Karen P. Steel; Sven Enerbäck Mice that lack the winged helix/forkhead gene Foxi1 (also known as Fkh10 ) are deaf and display shaker/waltzer behavior, an indication of disturbed...
Journal Articles
Journal: Development
Development (2003) 130 (5): 929–940.
Published: 01 March 2003
... otic primordia. Here, we identify a mutation in zebrafish, hearsay , which disrupts the initiation of placode formation. We show that hearsay disrupts foxi1 , a forkhead domain-containing gene, which is expressed in otic precursor cells before placodes become visible; foxi1 appears to be the earliest...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2397–2406.
Published: 15 June 2001
...Margit Mahlapuu; Sven Enerbäck; Peter Carlsson The murine Foxf1 gene, encoding a forkhead – or winged helix – transcription factor, is expressed in splanchnic mesenchyme during organogenesis. The concentration of expression to subepithelial mesenchyme suggested that Foxf1 is activated by paracrine...