... factors. Here, we show that repression of Sgs expression is indirectly controlled by the BR-C through transcriptional down-regulation of fork head , a tissue-specific gene that plays a central role in salivary gland development and is required for Sgs expression. Our results demonstrate that integration...

... constriction. In embryos mutant for fork head ( fkh ), which encodes a transcription factor homologous to mammalian hepatocyte nuclear factor 3β (HNF-3β), the secretory primordia are not internalized and secretory tubes do not form. Here, we show that secretory cells of fkh mutant embryos undergo extensive...

...Kristy L. Kenyon; Sally A. Moody; Milan Jamrich Xlens1 is a novel Xenopus member of the fork head gene family, named for its nearly restricted expression in the anterior ectodermal placode, presumptive lens ectoderm (PLE), and anterior epithelium of the differentiated lens. The temporal and spatial...

... are achieved by the function of caudal in activating different target genes, namely folded gastrulation , which is required for invagination of the posterior gut primordium, and fork head and wingless , which are required to promote development of the internalized hindgut primordium. caudal is not sufficient...

... the medial mammillary nucleus. These results suggest that Fkh5 plays a major role during CNS development. 06 09 1997 © 1997 by Company of Biologists 1997 Fkh5 fork head winged helix midbrain inferior colliculi hypothalamus mammillary body mouse One attempt to understand...

... of parasegment 2, is among the earliest to be defined. It is soon divided into two distinct regions: the more dorsal pregland cells and the more ventral preduct cells. We show that it is the opposing activities of the Drosophila EGF receptor (DER) signaling pathway and the Fork head transcription factor...