... and discussing how they function. Forkhead Fox Foregut development Language acquisition Pioneer factors Transcription factors The forkhead ( fkh ) gene was originally identified in a random mutagenesis screen performed in Drosophila melanogaster ( Weigel et al., 1989 ). This study showed...

... for correspondence (e-mail: b.hogan@cellbio.duke.edu ) 31 3 2009 © 2009. 2009 Sox2 Foregut development Trachea Epithelial-mesenchymal interaction Epithelial differentiation Injury-repair Mouse The anterior foregut of the mammalian embryo initially consists of a simple epithelial...

... growth factor Tgfβ Transforming growth factor Lung development Foregut development Organogenesis Mouse Raldh2 ( Aldh1a2 ) During foregut development, activation of morphogenetic programs in the pre-patterned endoderm gives rise to a number of gut-derived organs, including the lung...

... defects in foregut development. However, at P0 all Sox2 EGFP/COND compound mutants showed labored breathing and died with air in the stomach. In approximately 60% of these mutants this phenotype might have resulted from the presence of TEF (see below). However,all the Sox2 EGFP/LP mutants also died...