... termini, but the cause of this phenotype remains unclear. Here, we show that the β-integrin Myospheroid (Mys) is only required during early oogenesis when the pre-follicle cells form the FE. Mutation of mys disrupts both the formation of a monolayered epithelium at egg chamber termini...

... family of vertebrate proto-oncogenes, which synergizes with daughters against dpp and brinker to set the posterior and lateral limits of the region, giving rise to dorsal follicle cells. * Author for correspondence (e-mail: [email protected] ) 23 3 2007 © 2007. 2007...

...Efrat Assa-Kunik; Isabel L. Torres; Eyal D. Schejter; Daniel St Johnston; Ben-Zion Shilo The specification of polar, main-body and stalk follicle cells in the germarium of the Drosophila ovary plays a key role in the formation of the egg chamber and polarisation of its anterior-posterior axis. High...

...- and negative-feedback regulation generates two dorsolateral follicle cell primordia that will produce the eggshell appendages. A dorsal midline domain of low Egfr activity between the appendage primordia defines their dorsal boundary, but little is known about the mechanisms that establish their ventral limit...

...Jennifer C. Adam; Denise J. Montell The Drosophila ovary provides a model system for studying the mechanisms that regulate the differentiation of somatic stem cells into specific cell types. Ovarian somatic stem cells produce follicle cells, which undergo a binary choice during early...

...Halyna R. Shcherbata; Cassandra Althauser; Seth D. Findley; Hannele Ruohola-Baker The Notch signaling pathway controls the follicle cell mitotic-to-endocycle transition in Drosophila oogenesis by stopping the mitotic cycle and promoting the endocycle. To understand how the Notch pathway coordinates...

... Fas III(C,C′) as well as α-Spectrin (D,D′) at high levels compared with adjacent follicle cells. Empty arrowhead (C) points to one Sce 1 cell (four other Sce 1 cells are present in this stalk). (E-E′) Mosaic Sce 1 /Sce + follicle. Sce 1 follicular cells strongly express Fas III protein...

...Tripti Gupta; Trudi Schüpbach Patterning of the Drosophila egg requires cooperation between the germline cells and surrounding somatic follicle cells. In order to identify genes involved in follicle cell patterning, we analyzed enhancer trap lines expressed in specific subsets of follicle cells...

...-associated proteins. This is not the case in Drosophila , however, as null mutations in the single tau family member in the genome have no effect on the microtubule organisation in the follicle cells. Furthermore, PAR-1 activity stabilises microtubules, as microtubules in mutant cells depolymerise much more...

.... The level of dome activity is critical for proper border cell migration and is controlled in part through a negative feedback loop. In addition to its essential role in border cells, we show that dome is required in the germarium for the polarization of follicle cells during encapsulation of germline cells...

... oogenesis. The gene for a JAK pathway ligand, unpaired , is expressed specifically in the polar follicle cells, two pairs of somatic cells at the anterior and posterior poles of the developing egg chamber. Consistent with unpaired expression, reduced JAK pathway activity results in the fusion of developing...

... to endocycle is regulated is poorly understood. We show that the transition from mitotic cycle to endocycle in the Drosophila follicle cell epithelium is regulated by the Notch pathway. Loss of Notch function in follicle cells or its ligand Delta function in the underlying germline disrupts the normal...

... ( Fig. 3 E) that is more difficult to detect convincingly above background by in situ hybridization. In addition, some enhancer trap staining is detected in main body follicle cells up to stage 3; we attribute this to the broad transcription of fng in the germarium, and the perdurance of β...

...: Biological Sciences, University of Kentucky, 101 TH Morgan Building, Lexington, KY 40506, USA 17 02 1998 19 05 1998 © 1998 by Company of Biologists 1998 Drosophila mosaics UAS-FLP follicle cells oogenesis Previous work from a number of laboratories has provided...

... , a gene encoding zinc-finger transcription factors, is essential for the morphogenesis of dorsal appendages and is expressed in a bilaterally symmetrical pattern in the lateral-dorsal-anterior follicle cells during late oogenesis. This is induced and specified along the dorsoventral axis by an epidermal...

... oogenesis. It is localized at the oocyte-follicle cell contacts suggesting that it functions in the adhesion of the two cell types. When oocytes mature and the contacts to the follicle cells break, U-cadherin disappears from the oocyte surface. Evidence for a translocation of U-cadherin from the membrane...

...Paul S. Burgoyne; Mia Buehr; Anne Mclaren Oocytes with adhering follicle cells were sampled from ovaries obtained from 11 GPI-1A↔GPI-1B chimaeras, comprising 10 females and 1 hermaphrodite. GPI analysis of individual oocytes revealed a marked bias towards the GPI-1B component in the germ line...

...Johan Geysen; Johan Cardoen; Arnold De Loof ABSTRACT In S. bullata , the ovaries contribute to the synthesis of yolk polypeptides. A specific antiserum for yolk polypeptides was used to visualize the presence of yolk polypeptides in the follicle cells during their differentiation. After...

... characteristically stain intercellular materials of the developing embryo and may therefore be valid for studying cellular construction of the embryo. Furthermore, monoclonal antibodies that recognize components of follicle cells, perivitelline space and sperm have also been established. References Galfre...