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Keywords: Flk1 (Kdr)
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Journal Articles

Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse

Hiroyuki Ishitobi, Asami Wakamatsu, Fang Liu, Takuya Azami, Michito Hamada, Ken Matsumoto, Hiroshi Kataoka, Makoto Kobayashi, Kyunghee Choi, Shin-ichi Nishikawa, Satoru Takahashi, Masatsugu Ema
Journal: Development
Development (2011) 138 (24): 5357–5368.
https://doi.org/10.1242/dev.065565
Published: 15 December 2011
... contributed equally to this work Competing interests statements The authors declare no competing financial interests. 5 10 2011 © 2011. Cardiogenesis Flk1 (Kdr) Hemangioblasts Hematopoiesis VEGF Vasculogenesis Mouse Mesodermal cells give rise to blood...
View articletitled, Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse
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Includes: Supplementary data
Journal Articles

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation

Changwon Park, Kory Lavine, Yuji Mishina, Chu-Xia Deng, David M. Ornitz, Kyunghee Choi
Journal: Development
Development (2006) 133 (17): 3473–3484.
https://doi.org/10.1242/dev.02499
Published: 1 September 2006
... established that cells of the circulatory system develop from FLK1 + mesoderm. FLK1 (KDR -Mouse Genome Informatics) is a receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF). In primitive streak stage embryos, Flk1 expression is first detectable in the extra-embryonic mesoderm...
View articletitled, Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation
Open the PDF for Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation in another window
Includes: Supplementary data