..., parapineal neurons migrate unilaterally away from the rest of the pineal complex whereas rods, cones and projection neurons are non-migratory. The transcription factor Tbx2b is important for both the correct number and migration of parapineal neurons. We find that two additional transcription factors, Flh...

... (A); cyc;flh double mutant at 24 h (B); flh;syu double mutant at 18-19 h (C); and cyc;syu double mutant at 18-19 h (D). Scale bar: 50 μm. Fig. 4. Ehh is less effective than Shh and Twhh for primary motoneuron formation. Lateral views of islet1 + islet2 expression (both in blue) in wild-type embryo...

... of early mesodermal inducers ( activin and ntl ) and reveal an autoregulatory feedback loop between ntl and tbx-c . These data and analysis of midline ( ntl − / − and flh − / − ) and lateral mesoderm ( spt − / − ) mutants suggest that tbx-c may function during formation of the notochord. * Author...