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Keywords: Fin
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Journal Articles
Journal: Development
Development (2021) 148 (16): dev197244.
Published: 16 August 2021
... elements. Irx Cartilage Craniofacial skeleton Fin Zebrafish National Institute of Dental and Craniofacial Research http://dx.doi.org/10.13039/100000072 R35 DE027550 Helen Hay Whitney Foundation http://dx.doi.org/10.13039/100005237 Howard Hughes Medical...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (13): 2581–2591.
Published: 1 July 2014
... amputation of the tail fin, and detailed a migratory timecourse that revealed conserved elements of the inflammatory cell response with mammals. Next, we used transgenic zebrafish in which we could selectively ablate macrophages, which allowed us to investigate whether macrophages were required for tail fin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (18): 3754–3764.
Published: 15 September 2013
...Gregory Nachtrab; Kazu Kikuchi; Valerie A. Tornini; Kenneth D. Poss Many fish and salamander species regenerate amputated fins or limbs, restoring the size and shape of the original appendage. Regeneration requires that spared cells retain or recall information encoding pattern, a phenomenon termed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (12): 2210–2220.
Published: 15 June 2012
... Repressive Complex 1 (PRC1), is essential for pectoral fin development. We show that differentiation of lateral plate mesoderm (LPM) cells into presumptive pectoral fin precursors is initiated normally in ring1b mutants, but fin bud outgrowth is impaired. Fgf signaling, which is essential for migration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (6): 871–879.
Published: 15 March 2010
... then activates IGF signaling specifically in cells of the adjacent apical epithelium. Inhibition of IGF signaling by either morpholino antisense technology, or by specific chemical inhibitors of Igf1 receptor function NVP-AEW541 and NVP-ADW742, impairs fin regeneration. At the cellular level, this block...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (18): 3063–3070.
Published: 15 September 2008
...,appendage regeneration has been studied extensively, the extent to which homeostatic regeneration maintains these structures has not been examined. Here, we found that transgenic inhibition of Fgf receptors in uninjured zebrafish caused severe atrophy of all fin types within 2 months, revealing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (23): 5173–5183.
Published: 1 December 2005
... of growth during zebrafish caudal fin regeneration. These growth rates correlate with position-dependent differences in blastemal length, mitotic index and expression of the Fgf target genes mkp3 , sef and spry4 . To address whether PD differences in amounts of Fgf signaling are responsible for position...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (22): 5141–5149.
Published: 15 November 2002
...-sensitive defects in adult fin regeneration. The nightcap mutant showed a defect in fin regeneration that was first apparent at the onset of regenerative outgrowth. Positional cloning revealed that nightcap encodes the zebrafish orthologue of mps1 , a kinase required for the mitotic checkpoint. mps1...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1994) 120 (7): 1861–1872.
Published: 1 July 1994
... of one of the zebrafish RARs that is the predominant receptor in the regenerating caudal fin and corresponds most closely to the RAR-γ subtype isolated from mouse and human and to RAR-δ from newt. Zebrafish RAR-γ (zfRAR-γ) exhibits both structural and functional conservation with its mammalian...
Journal Articles
Journal: Development
Development (1994) 1994 (Supplement): 169–180.
Published: 1 January 1994
... limb evolution. The rich fossil record of vertebrate fins/limbs, although restricted to skeletal tissues, exceeds the morphological diversity of the extant biota, and a systematic approach to limb evolution produces an informative picture of evolutionary change. A composite framework of several...