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Keywords: Fibrosis
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Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2024) 151 (15): dev203124.
Published: 31 July 2024
...Marcos Sande-Melon; David Bergemann; Miriam Fernández-Lajarín; Juan Manuel González-Rosa; Andrew G. Cox ABSTRACT The liver is a remarkable organ that can regenerate in response to injury. Depending on the extent of injury, the liver can undergo compensatory hyperplasia or fibrosis. Despite decades...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (24): dev201976.
Published: 21 December 2023
... populations, due to a combination of delayed mitosis, increased apoptosis and premature differentiation of progenitor cells. These defects resulted in dysplastic kidneys at birth, which rapidly formed cysts, displayed increased interstitial fibrosis and decline in kidney function. RNA sequencing of embryonic...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2020) 147 (4): dev167718.
Published: 25 February 2020
... have learnt about principles of regeneration from this new model. Spiny mouse Acomys Tissue regeneration Fibrosis Scarring The field of regenerative medicine aims to identify strategies to either engineer or repair human tissues, organs and body parts that cannot naturally...
Journal Articles
Journal: Development
Development (2011) 138 (17): 3625–3637.
Published: 1 September 2011
... of these cells for regeneration has not been tested. Connective tissue fibroblasts also are likely to play a role in regeneration, as connective tissue fibrosis is a hallmark of regenerating muscle. However, the lack of molecular markers for these fibroblasts has precluded an investigation of their role. Using...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (9): 1663–1674.
Published: 1 May 2011
... ventricular wall, suggesting that regeneration is associated with processes resembling mammalian ventricular remodeling after acute MI. Our results provide the first evidence that, like mammalian hearts, teleost hearts undergo massive fibrosis after cardiac damage. Unlike mammals, however, the fish heart can...
Includes: Multimedia, Supplementary data