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Keywords: Fibroblasts
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Journal: Development
Development (2022) 149 (20): dev199723.
Published: 24 June 2022
... potential of contaminating undifferentiated pluripotent cells, are major bottlenecks towards their translational utility. Here, we report the rapid generation of human oligodendrocytes by direct lineage conversion of human dermal fibroblasts (HDFs). We show that the combination of the four transcription...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2016) 143 (3): 387–397.
Published: 1 February 2016
... to replace the scar and rebuild normal functioning tissue. Here, we address this problem in the context of heart disease, and discuss the origins and characteristics of cardiac fibroblasts, as well as the crucial role that they play in cardiac development and disease. We discuss the dual nature of cardiac...
Journal Articles
Journal: Development
Development (2013) 140 (7): 1517–1527.
Published: 1 April 2013
...Barbara A. Schmidt; Valerie Horsley Acute wound healing in the skin involves the communication of multiple cell types to coordinate keratinocyte and fibroblast proliferation and migration for epidermal and dermal repair. Many studies have focused on the interplay between hematopoietic cells...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (1989) 105 (3): 585–593.
Published: 1 March 1989
..., is also normal. Fibroblast condensations that may represent sets of these cells normally associated with muscles in the extensor and flexor compartments of the carpal region also form in muscleless limbs. The results are discussed in terms of the importance of the dermis in pattern regulation...
Journal Articles
Journal: Development
Development (1986) 97 (1): 111–124.
Published: 1 September 1986
... epidermis of amputated adult rat vibrissa follicles. Amputated follicles that received no cell implants or implants of cultured dorsal skin fibroblasts were used as controls. Over 50 % of follicles implanted with cultured papilla cells in the passage range 1 –3 grew hairs. In contrast none of the follicles...