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Keywords: Fertilization
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Journal Articles
Journal: Development
Development (2020) 147 (15): dev189985.
Published: 14 August 2020
... the cortical actin cap region of the oocyte, thus confining GPI-APs to the appropriate fusion site. Oocyte Fertilization GPI-anchored proteins (GPI-APs) Microvilli CD9 JUNO In multiple phases of mammalian gamete fusion, IZUMO1 ( Inoue et al., 2005 ) and its receptor JUNO (also known...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (15): dev190777.
Published: 07 August 2020
... developmental potential of these RRF-reduced oocytes with MII-spindle shrinkage was not lost after fertilization. When somatic cell nuclear transfer was performed, the successful generation of cloned mice was somewhat improved and abnormalities were reduced when oocytes with slightly reduced RRF levels were...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2020) 147 (8): dev183715.
Published: 27 April 2020
... specific 1 is essential for angiosperm fertilization . Nat. Cell Biol.   8 , 64 - 71 . 10.1038/ncb1345 Pleskot , R. , Pejchar , P. , Bezvoda , R. , Lichtscheidl , I. K. , Wolters-Arts , M. , Marc , J. , Žárský , V. and Potocký , M. ( 2012 ). Turnover of...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (22): dev167023.
Published: 22 November 2018
... teleosts, fertilization occurs through the micropyle, a funnel-like opening in the chorion, formed by a unique enlarged follicle cell, the micropylar cell (MC). We describe here, for the first time, the mechanism that underlies the differentiation of the MC. Our genetic analyses show that Taz is essential...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (1): dev152645.
Published: 08 January 2018
... fertilization products. Blocking the initial unequal division genetically, we first highlight that the default differentiation state after male meiosis is a vegetative fate, which is consistent with earlier work. We find that uni-nucleated mutant microspores differentiated as wild-type vegetative cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4481–4495.
Published: 15 December 2017
...Javier M. Hernández; Benjamin Podbilewicz Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the...
Journal Articles
In collection:
Plant development
Journal: Development
Development (2017) 144 (8): 1490–1497.
Published: 15 April 2017
...Olivier Coen; Elisa Fiume; Wenjia Xu; Delphine De Vos; Jing Lu; Christine Pechoux; Loïc Lepiniec; Enrico Magnani Angiosperm seed development is a paradigm of tissue cross-talk. Proper seed formation requires spatial and temporal coordination of the fertilization products – embryo and endosperm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (15): 2780–2790.
Published: 01 August 2016
...Marta Adelina Mendes; Rosalinda Fiorella Guerra; Beatrice Castelnovo; Yuriria Silva-Velazquez; Piero Morandini; Silvia Manrique; Nadine Baumann; Rita Groß-Hardt; Hugh Dickinson; Lucia Colombo Fertilization in flowering plants requires a complex series of coordinated events involving interaction...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1705–1716.
Published: 01 May 2015
... mitochondria has also been observed in mouse and fly embryos but their role in degradation is debated. Both worm Atg8 ubiquitin-like proteins, LGG-1/GABARAP and LGG-2/LC3, are recruited around sperm organelles after fertilization. Whereas LGG-1 depletion affects autophagosome function, stabilizes the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3732–3739.
Published: 01 October 2014
... fusion during mammalian fertilization. After initial contact, adhesion between gametes only leads to fusion in the presence of three membrane proteins that are necessary, but insufficient, for fusion: Izumo1 on sperm, its receptor Juno on egg and Cd9 on egg. What happens during this adhesion phase is a...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1705–1714.
Published: 15 April 2014
... these events. Inhibition of fertilization by anti-UPIII antibody is rescued by co-incubation with UF-MDs. This suggests that, like MDs in intact eggs, the isolated UF-MDs are capable of interacting with sperm, an interaction that does not interfere with normal fertilization but rather augments the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4471–4479.
Published: 15 November 2013
...Masaru Okabe Fertilization is the process by which eggs and spermatozoa interact, achieve mutual recognition, and fuse to create a zygote, which then develops to form a new individual, thus allowing for the continuity of a species. Despite numerous studies on mammalian fertilization, the molecular...
Journal Articles
Journal: Development
Development (2011) 138 (5): 885–895.
Published: 01 March 2011
...Rémi Dumollard; Mark Levasseur; Céline Hebras; Philippe Huitorel; Michael Carroll; Jean-Philippe Chambon; Alex McDougall Mos kinase is a universal mediator of oocyte meiotic maturation and is produced during oogenesis and destroyed after fertilization. The hallmark of maternal meiosis is that two...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (16): 2683–2690.
Published: 15 August 2010
...Sze Jet Aw; Yuki Hamamura; Zhong Chen; Arp Schnittger; Frédéric Berger Fertilization in flowering plants involves two sperm cells and two female gametes, the egg cell and the central cell, progenitors of the embryo and the endosperm, respectively. The mechanisms triggering zygotic development are...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (24): 4077–4081.
Published: 15 December 2009
... ( Knott et al., 2006 ; Madgwick et al., 2005 ). CamKII is therefore thought to be the downstream kinase activated by the sperm Ca 2+ signal at fertilization. Here, we sought to determine which CamKII family members are present in eggs, and to determine the effects of their knockdown on cell cycle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (19): 3279–3288.
Published: 01 October 2009
... their growth within maternal tissues until they reach the female gametophytes. Upon arrival, the female FER -dependent signaling cascade is activated to mediate pollen tube reception and fertilization, while male ANX -dependent signaling is deactivated, enabling the pollen tube to rupture and deliver...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (11): 1835–1847.
Published: 01 June 2009
...Julian L. Wong; Gary M. Wessel Fertilization is accompanied by the construction of an extracellular matrix that protects the new zygote. In sea urchins, this structure is built from glycoproteins residing at the egg surface and in secretory vesicles at the egg cortex. Four enzymatic activities are...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (10): 1687–1696.
Published: 15 May 2009
... arrest is released by fertilization. However, it remains unclear how release from the meiotic arrest is implicated in the start of the embryonic cell cycle. To elucidate this link, we have used starfish eggs, in which G1 phase arrest occurs after completion of meiosis if the mature oocytes are not...
Journal Articles
Journal: Development
Development (2008) 135 (24): 4123–4130.
Published: 15 December 2008
... activated after fertilization, beginning ∼4 hours post-egg activation and reaching a maximum by ∼10 hours. One- and 2-cell embryos contained endogenous betaine, indicating that a likely function for the transporter in vivo is the accumulation or retention of intracellular betaine. The appearance of...
Journal Articles
Journal: Development
Development (2008) 135 (11): 2001–2011.
Published: 01 June 2008
.... Significantly, in vitro fertilization of COC-enclosed oocytes was reduced by the TLR2/TLR4 neutralizing antibodies or by Pep-1. From these results, we propose that TLR2 and TLR4 present on cumulus cells were activated by the co-culture with sperm in a hyaluronan fragment-dependent manner, and that chemokines...
Includes: Supplementary data