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Keywords: Feed-forward loop
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Journal Articles

A developmental stage-specific network approach for studying dynamic co-regulation of transcription factors and microRNAs during craniofacial development

Fangfang Yan, Peilin Jia, Hiroki Yoshioka, Akiko Suzuki, Junichi Iwata, Zhongming Zhao
Journal: Development
Development (2020) 147 (24): dev192948.
https://doi.org/10.1242/dev.192948
Published: 24 December 2020
... . Int. J. Neuropsychopharmacol.   14 , 567 - 572 . 10.1017/S1461145710001446 Jiang , W. , Mitra , R. , Lin , C.-C. , Wang , Q. , Cheng , F. and Zhao , Z. ( 2016 ). Systematic dissection of dysregulated transcription factor–mirna feed-forward loops across tumor types...
View article titled, A developmental stage-specific network approach for studying dynamic co-regulation of transcription factors and microRNAs during craniofacial development
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Includes: Supplementary data
Journal Articles

EGFR-dependent network interactions that pattern Drosophila eggshell appendages

David S. A. Simakov, Lily S. Cheung, Len M. Pismen, Stanislav Y. Shvartsman
Journal: Development
Development (2012) 139 (15): 2814–2820.
https://doi.org/10.1242/dev.077669
Published: 1 August 2012
... model of follicle cell patterning. Based on the computational model analysis, we propose that dorsal appendage primordia are established by sequential action of feed-forward loops and juxtacrine signals activated by the gradient of EGFR signaling. The model describes pattern formation in a large number...
View article titled, EGFR-dependent network interactions that pattern Drosophila eggshell appendages
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Journal Articles

The LEAFY target LMI1 is a meristem identity regulator and acts together with LEAFY to regulate expression of CAULIFLOWER

Louis A. Saddic, Bärbel Huvermann, Staver Bezhani, Yanhui Su, Cara M. Winter, Chang Seob Kwon, Richard P. Collum, Doris Wagner
Journal: Development
Development (2006) 133 (9): 1673–1682.
https://doi.org/10.1242/dev.02331
Published: 1 May 2006
... of LFY. Here, we demonstrate that one of these, the class I homeodomain leucine-zipper transcription factor LMI1, is a meristem identity regulator. LMI1 acts together with LFY to activate CAL expression. The interaction between LFY, LMI1 and CAL resembles a feed-forward loop transcriptional network motif...
View article titled, The LEAFY target LMI1 is a meristem identity regulator and acts together with LEAFY to regulate expression of CAULIFLOWER
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Includes: Supplementary data