... Neocortex Pathfinding Adhesion Fasciculation Cadherin During development, axons with similar destinations form bundles and pathways in the central nervous system (CNS). In the mammalian neocortex, afferent and efferent fibers, which connect the subcortical and cortical regions, form layers...

... known. Here, we show that neutralization of neuronal Nogo-A or Nogo-A gene ablation (KO) leads to longer neurites, increased fasciculation, and decreased branching of cultured dorsal root ganglion neurons. The same effects are seen with antibodies against the Nogo receptor complex components NgR...

... vertebrate tracts. References Bak, M. and Fraser, S. E. ( 2003 ). Axon fasciculation and differences in midline kinetics between pioneer and follower axons within commissural fascicles. Development 130 , 4999 -5008. Bate, C. M. ( 1976 ). Pioneer neurones in an insect embryo. Nature 260...

... fasciculation/defasciculation of motor axons in the CNS and for normal guidance of many motor axons enroute to their muscle targets. Tlr belongs to a family of developmentally important proteases that process various extracellular matrix components, as well as several TGF-β inhibitory proteins and pro-peptides...

... growth cones,which is required for topographic map formation. * Author for correspondence (e-mail: [email protected] ) 29 10 2004 ©2005. 2005 Retinotectal projection Topographic mapping Fasciculation Axon branching Visual system Zebrafish For an animal to see well...

..., H. and Axel, R. ( 1994 ). Allelic inactivation regulates olfactory receptor gene expression. Cell 78 , 823 -834. Cloutier, J.-F., Giger, R., Koentges, G., Dulac, C., Kolodkin,A. L. and Ginty, G. G. ( 2002 ). Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal...

...Timothy P. Newsome; Bengt Åsling; Barry J. Dickson ABSTRACT During development of the adult Drosophila visual system, axons of the eight photoreceptors in each ommatidium fasciculate together and project as a single bundle towards the optic lobes of the brain. Within the brain, individual...

... the same muscle for much of their course. This suggests that muscle sensory axons may be guided to the appropriate muscles by fasciculating along motoneuron axons. Taken together, the results show that sensory axons projecting along different nerves are different from one another and respond to cues...

...Bruce Wightman; Renee Baran; Gian Garriga ABSTRACT During nervous system development, growth cone pioneering and fasciculation contribute to nerve bundle structure. Pioneer growth cones initially navigate along neuroglia to establish an axon scaffold that guides later extending growth cones. In C...

... outgrowth and fasciculation. Once established, the primary axon scaffold of the brain is used for fasciculation by subsequently differentiating neurons and, by the 40% stage of embryogenesis, axonal projections that characterize the mature brain become evident. The single cell analysis of grasshopper brain...

... © 1993 by Company of Biologists 1993 C. elegans axonal outgrowth axonal branching fasciculation A major goal in developmental neurobiology is to under-stand how neurites navigate to find their synaptic partners. What types of cells guide neurites to their targets? What...