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Keywords: FMRP
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (10): dev200379.
Published: 20 May 2022
... the Drosophila fragile X mental retardation protein (FMRP), a conserved RNA-binding protein, limits dendrite branching to ensure proper neuronal function during larval sensory neuron development. FMRP knockdown causes increased dendritic terminal branch growth and a resulting overelaboration defect due, in part...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (9): dev200045.
Published: 3 May 2022
...Chunzhu Song; Shannon N. Leahy; Emma M. Rushton; Kendal Broadie ABSTRACT Both mRNA-binding Fragile X mental retardation protein (FMRP; Fmr1) and mRNA-binding Staufen regulate synaptic bouton formation and glutamate receptor (GluR) levels at the Drosophila neuromuscular junction (NMJ) glutamatergic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev196568.
Published: 7 January 2021
... mapped the targets of the more selective RNA binder, Fragile X mental retardation protein (FMRP), using enhanced crosslinking and immunoprecipitation (eCLIP), and report for the first time its binding motif in Drosophila cells. This method will therefore enable the RNA profiling of wild-type and mutant...
Includes: Supplementary data