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Keywords: FGFR2
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Journal Articles
Journal: Development
Development (2022) 149 (1): dev200021.
Published: 12 January 2022
... progenitors of the distal ureteric bud. Urothelial development requires signaling input from surrounding mesenchymal cells, which, in turn, depend on cues from the epithelial primordium to form a layered fibro-muscular wall. Here, we have identified FGFR2 as a crucial component in this reciprocal signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev166454.
Published: 16 January 2019
... and Fgf10 signaling, suggesting a cytoplasmic role for Yap in epithelial lineage commitment. Lung Hippo Yap Fgfr2 Ilk Fgf10 Integrin β-Catenin Differentiation Progenitor The mammalian lung has a well-designed anatomical structure that allows for efficient gas exchange: an arborized...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3777–3788.
Published: 15 October 2017
... pathway to FGF stimulation. Mammary stem cells Branching morphogenesis PTPRB FGFR2 Terminal end bud gene expression Mouse The mammary gland is a highly dynamic organ; limited embryonic development is followed by extensive postnatal pubertal development with further differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (17): 3352–3362.
Published: 1 September 2014
... are not well understood. Here, we have examined the requirement of Fgfr2 in mouse mammary gland morphogenesis using a postnatal organ regeneration model. We found that tissue regeneration from basal stem cells is a multistep event, including luminal differentiation and subsequent epithelial branching...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (2): 353–365.
Published: 15 January 2008
... ectopically throughout most of the ectoderm. Inhibition of either FGFA, FGFR1 or FGFR2 function severely affects morphogenesis of the skeleton. Furthermore,inhibition of FGFA and FGFR1 signaling dramatically delays invagination of the archenteron, prevents regionalization of the gut and abrogates formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 557–565.
Published: 1 February 2007
... branching, the svs mutation dramatically reduces branching without reducing organ growth. Using a positional cloning approach, we identified the svs mutant lesion as a 491 bp insertion in the tenth intron of Fgfr2 that results in changes in the pattern of Fgfr2 alternative splicing. An engineered null...
Journal Articles
Journal: Development
Development (2005) 132 (13): 2981–2990.
Published: 1 July 2005
...Thomas Schlake Reciprocal interactions between the dermal papilla and the hair matrix control proliferation and differentiation in the mature hair follicle. Analysis of expression suggests an important role for FGF7 and FGF10, as well as their cognate receptor FGFR2-IIIb, in these processes...
Includes: Supplementary data
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Journal: Development
Development (1994) 120 (5): 1335–1346.
Published: 1 May 1994
... for correspondence * Authors contributed equally 31 January 1994 © 1994 by Company of Biologists 1994 msd mouse mutants mesoderm induction Brachyury ( T ) Evx1 goosecoid Fgf4 Fgf5 Fgfr1 Fgfr2 Sna H19 The morphogenetic movements of gastrulation...
Journal Articles