... transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid . Cell 67 , 89 - 104 . 10.1016/0092-8674(91)90574-I Koziczak , M. , Holbro , T. and Hynes , N. E. ( 2004 ). Blocking of FGFR signaling inhibits breast cancer cell proliferation...

... neural crest (CNC) cell proliferation Differentiation Frontal bone development DLX5 FGFR TGFβ Twist1 Mouse Skull vault malformations are a major group of congenital birth defects in humans. The cranial neural crest (CNC), a population of multipotent embryonic progenitor...

...) EGL-17, an attractant for the migrating sex myoblasts (SMs), repels the CANs, a pair of neurons that migrate posteriorly from the head to the center of the embryo. Although mutations in genes encoding EGL-17/FGF and a specific isoform of its receptor EGL-15/FGFR had little effect on CAN migration...

...Stefanie Sudhop; Francois Coulier; Annette Bieller; Angelika Vogt; Tobias Hotz; Monika Hassel Signalling through fibroblast growth factors (FGFR) is essential for proper morphogenesis in higher evolved triploblastic organisms. By screening for genes induced during morphogenesis in the diploblastic...

...Sonya C. Faber; Patricia Dimanlig; Helen P. Makarenkova; Sanjay Shirke; Kyung Ko; Richard A. Lang We describe experiments showing that fibroblast growth factor receptor (Fgfr) signaling plays a role in lens induction. Three distinct experimental strategies were used: (1) using small-molecule...

... together, these findings suggest that the responsiveness of Shh to FGF is mediated, at least in part, by PKCs. *Author for correspondence ( [email protected] ) 17 4 2001 © 2001. 2001 FGF FGFR Protein kinase C RACK1 Retinoids Sonic hedgehog Chick Numerous...

... ) 26 3 2001 © 2001. 2001 BMP Sprouty4 FGF3 FGF8 FGFR ERK MAPK Ras Morpholino Zebrafish Throughout embryonic and adult life, members of the fibroblast growth factor (FGF) family of secreted signaling molecules are implicated in the regulation of cell survival...

... of the role that growth factors might play in this process. The discovery that mutations in fibroblast growth factor receptors (FGFRs) cause the major craniosynostosis syndromes implicates FGF-mediated signalling in the skeletogenic differentiation of the cranial neural crest. We now show that, in vitro...

[email protected] ) 06 04 2000 08 02 2000 © 2000 by Company of Biologists 2000 TWIST FGF Craniosynostosis Suture ID FGFR BMP Intramembranous bone formation Mouse Human Except for the supraoccipital bone, the majority of the calvarial bones form by intramembranous...

.... The mobility of relevant DNA molecular weight standards (1 kb ladder, Gibco/BRL) are indicated by arrowheads. * Author for correspondence 21 09 1995 © 1995 by Company of Biologists 1995 FGF FGFR lens transgenic dominant negative mouse Elucidation of the function...

... FGFR FGF receptors brain development limb development mouse embryogenesis oncogenes pharyngeal arches tyrosine kinase receptors alternative splicing The mammalian Fibroblast Growth Factor (FGF) family consists of at least nine related genes that are classified as members on the basis...