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Keywords: FGFR
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Journal Articles
Journal: Development
Development (2023) 150 (1): dev201036.
Published: 6 January 2023
... regeneration in aged degenerated discs in zebrafish. Thus, CCN2 could be exploited for therapeutic intervention in degenerated human discs. Intervertebral disc CCN2 Zebrafish Regeneration FGFR SHH The Wellcome Trust DBT India Alliance https://dx.doi.org/10.13039/501100009053 IA/I/18/2...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (21): 4857–4867.
Published: 1 November 2005
...) EGL-17, an attractant for the migrating sex myoblasts (SMs), repels the CANs, a pair of neurons that migrate posteriorly from the head to the center of the embryo. Although mutations in genes encoding EGL-17/FGF and a specific isoform of its receptor EGL-15/FGFR had little effect on CAN migration...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (22): 4425–4438.
Published: 15 November 2001
...Sonya C. Faber; Patricia Dimanlig; Helen P. Makarenkova; Sanjay Shirke; Kyung Ko; Richard A. Lang We describe experiments showing that fibroblast growth factor receptor (Fgfr) signaling plays a role in lens induction. Three distinct experimental strategies were used: (1) using small-molecule...
Journal Articles
Journal: Development
Development (2001) 128 (13): 2451–2460.
Published: 1 July 2001
..., R. E. and Tickle, C. ( 1991 ). Position-dependent expression of two related homeobox genes in developing vertebrate limbs. Nature 352 , 429 -431. Deng, C., Bedford, M., Li, C., Xu, X., Yang, X., Dunmore, J. and Leder, P. ( 1997 ). Fibroblast growth factor receptor-1 (FGFR-1) is essential...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2175–2186.
Published: 15 June 2001
... ) 26 3 2001 © 2001. 2001 BMP Sprouty4 FGF3 FGF8 FGFR ERK MAPK Ras Morpholino Zebrafish Throughout embryonic and adult life, members of the fibroblast growth factor (FGF) family of secreted signaling molecules are implicated in the regulation of cell survival...
Journal Articles
Journal: Development
Development (2001) 128 (11): 2143–2152.
Published: 1 June 2001
... of the role that growth factors might play in this process. The discovery that mutations in fibroblast growth factor receptors (FGFRs) cause the major craniosynostosis syndromes implicates FGF-mediated signalling in the skeletogenic differentiation of the cranial neural crest. We now show that, in vitro...
Journal Articles
Journal: Development
Development (2000) 127 (9): 1845–1855.
Published: 1 May 2000
...@operoni.helsinki.fi ) 06 04 2000 08 02 2000 © 2000 by Company of Biologists 2000 TWIST FGF Craniosynostosis Suture ID FGFR BMP Intramembranous bone formation Mouse Human Except for the supraoccipital bone, the majority of the calvarial bones form by intramembranous...
Journal Articles
Journal: Development
Development (1995) 121 (12): 3959–3967.
Published: 1 December 1995
... role in normal lens biology. * Author for correspondence 21 09 1995 © 1995 by Company of Biologists 1995 FGF FGFR lens transgenic dominant negative mouse Elucidation of the function of fibroblast growth factors (FGFs) during development is complicated...
Journal Articles
Journal: Development
Development (1995) 121 (11): 3603–3613.
Published: 1 November 1995
... ( Heikinheimo et al., 1994b ). The analysis of single FGF-8 isoforms that activate single FGFRs suggest a physiological role in normal development. However, it is also possible that heterodimerization of FGF-8 isoforms and/or FGFRs may occur and may be important for FGF signaling during mouse development...