... ), eyes absent ( eya ) and dachshund ( dac ) is initiated sequentially during the first and second larval instars ( Bonini et al., 1993 ; Cheyette et al., 1994 ; Mardon et al., 1994 ; Quiring et al., 1994 ; Czerny et al., 1999 ; Weasner et al., 2016 ). The stepwise activation of the RD network...

... ( hth )- eyes absent ( eya ) -sine oculis ( so ) -dachshund ( dac ) gene regulatory cassette is involved in this specification. Lamina neurons differentiate from NE progenitors that express hth , eya and so . One of the first events in the differentiation of lamina neurons is the upregulation of dac...

... and precursor cells are eliminated via apoptosis and as a result the surrounding head capsule proliferates to compensate for retinal tissue loss. This model implies that the sole responsibility of the RD network is to promote the fate of the eye. We have re-analyzed eyes absent mutant discs and propose...

... mesoderm development. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 16 2 2010 © 2010. 2010 FoxF FoxC let-381 Forkhead domain ceh-34 SIX2 homeodomain eya-1 Eyes absent...

... Decapentaplegic Eyes absent Homothorax Atonal During development, groups of cells become singled out as organ primordia through the combined action of organ-specific selector genes and a limited number of signaling pathways (reviewed by Mann and Morata, 2000 ). Nevertheless, the expression domains...

...Tobias Pauli; Makiko Seimiya; Jorge Blanco; Walter J. Gehring In Drosophila , the sine oculis ( so ) gene is important for the development of the entire visual system, including Bolwig's organ, compound eyes and ocelli. Together with twin of eyeless , eyeless , eyes absent and dachshund , so...

... does not fully explain the regulation of Fmrf . We have found that the Dachshund (Dac) and Eyes Absent (Eya)transcription co-factors participate in this combinatorial code. Previous studies have revealed an intimate link between Dac and Eya during eye development. Here, by analyzing their function...

.... In this report, we demonstrate that the retinal determination gene eyes absent ( eya ) is the crucial link between the Hedgehog signaling pathway and photoreceptor differentiation. Specifically, we show that the mechanism by which Hh signaling controls initiation of photoreceptor differentiation is to alleviate...

...-antennal disc that will become retina. We show that Wingless signalling establishes the border between the retina and adjacent head structures by inhibiting the expression of the eye specification genes eyes absent, sine oculis and dachshund . Ectopic Wingless signalling leads to the repression...

...Takashi Suzuki; Kaoru Saigo Bolwig’s organ is the larval light-sensing system consisting of 12 photoreceptors and its development requires atonal activity. Here, we showed that Bolwig’s organ formation and atonal expression are controlled by the concerted function of hedgehog, eyes absent and sine...

... is insensitive to wingless inhibition. The eyes absent and eyegone genes encode members of a group of nuclear proteins required to specify the fate of the eye imaginal disc. We show that both eyes absent and eyegone are required for normal activation of decapentaplegic expression at the posterior and lateral...

... oculis and eyes absent as two mediators of the eye-inducing activity of eyeless . We show that eyeless induces and requires the expression of both genes independently during extra eye development. During normal eye development, eyeless is expressed earlier than and is required for the expression of sine...

...Nancy M. Bonini; Quang T. Bui; Gladys L. Gray-Board; John M. Warrick ABSTRACT The fly eyes absent (eya) gene which is essential for compound eye development in Drosophila , was shown to be functionally replaceable in eye development by a vertebrate Eya homolog. The relationship between eya...

...-mail: [email protected] ) 26 12 1996 © 1997 by Company of Biologists 1997 Drosophila gonadogenesis clift eyes absent wingless bagpipe mesoderm The gonad forms during embryogenesis from germline and somatic cells. It is the interaction of these cells...

...Pin-Xian Xu; Ian Woo; Helen Her; David R. Beier; Richard L. Maas ABSTRACT We have identified and mapped three members of a new family of vertebrate genes, designated Eya1, Eya2 and Eya3 , which share high sequence similarity with the Drosophila eyes absent ( eya ) gene. Comparison of all three...