.... In the Drosophila eye imaginal disc, Wingless (Wg) signaling defines the region that gives rise to head tissue. JAK/STAT signaling was thought to regulate growth of the eye disc but not pattern formation. However, we show that the JAK/STAT pathway plays an important role in patterning the eye disc:it promotes...

... evolution. ‡ These authors contributed equally to the work * Author for correspondence (e-mail: maas@rascal.med.harvard.edu ) 23 10 1998 14 12 1998 © 1999 by Company of Biologists 1999 Pax6 Developmental expression Eye development Eye imaginal disc eyeless...

... has not been investigated. Here we show that Drosophila cyclin E (DmcycE) protein is absent in G 1 phase cells but appears at the onset of S phase in proliferating cells of the larval optic lobe and eye imaginal disc. We have examined cells in the eye imaginal epithelium, where a clearly defined...