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Keywords: Eye development
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Journal Articles
Journal: Development
Development (2020) 147 (24): dev185827.
Published: 23 December 2020
...’ called Pax6 , which is both necessary and sufficient for eye development. Yet precisely how Pax6 achieves this deeply homologous function is poorly understood. Using the chick as a model organism, we show that vertebrate Pax6 interacts with a pair of morphogen-coding genes, Tgfb2 and Fst , to form...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4673–4683.
Published: 15 December 2017
... during Drosophila eye development. Fizzy/Cdc20 controls the early growth of the eye disc anlage and the concomitant entry of glial cells onto the disc. In contrast, fzr/cdh1 acts during neuronal patterning and photoreceptor axon growth, and subsequently affects neuron-glia interaction. To further address...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (14): 2640–2651.
Published: 15 July 2017
... regulator of Eya-So in transcriptional outputs that coordinate cell cycle exit with the transition to differentiation during Drosophila retinal development. Eye development Cell cycle Transcription factor Retinal determination gene network Mitotic exit Development of a functional organ...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 321–333.
Published: 15 January 2017
... a direct interaction between Sipa1l3 and Epha4, building a functional platform for proper ocular development. Epha4 deficiency phenocopied loss of Sipa1l3 and rescue experiments demonstrated that Epha4 acts upstream of Sipa1l3 during eye development, with both Sipa1l3 and Epha4 required for early eye...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (2): 356–366.
Published: 15 January 2016
... of integrin- and FAK-mediated LE cell adhesion during lens development. Cataract Cell adhesion Cysteine-rich transmembrane BMP regulator 1 Crim1 Eye development Integrin Lens Mouse Summary: Crim1, a type I transmembrane protein, acts in lens epithelial cells where it colocalizes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 3021–3032.
Published: 01 September 2015
....   236 , 3088 - 3099 . 10.1002/dvdy.21343 Kwan , K. M. , Otsuna , H. , Kidokoro , H. , Carney , K. R. , Saijoh , Y. and Chien , C.-B. ( 2012 ). A complex choreography of cell movements shapes the vertebrate eye . Development   139 , 359 - 372 . 10.1242/dev.071407...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (14): 2487–2498.
Published: 15 July 2015
... by The Company of Biologists Ltd 2015 Summary: MicroRNAs expressed in the mouse RPE are dispensable for RPE specification and survival but are required for maturation and differentiation of the RPE and adjacent photoreceptors. RPE Dicer1 Dgcr8 MicroRNA Eye development Photoreceptor Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (13): 2746–2754.
Published: 01 July 2013
.... Published by The Company of Biologists Ltd 2013 EGFR signaling ETS proteins Pointed MAP kinase Eye development Development of all multicellular organisms is dictated by a handful of signaling pathways that transmit information from the extracellular milieu and neighboring cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 725–734.
Published: 01 March 2010
...Ke Tang; Xin Xie; Joo-In Park; Milan Jamrich; Sophia Tsai; Ming-Jer Tsai Transcriptional networks, which are initiated by secreted proteins, cooperate with each other to orchestrate eye development. The establishment of dorsal/ventral polarity, especially dorsal specification in the optic vesicle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (21): 3657–3667.
Published: 01 November 2009
.... Cytoplasmic protrusions connecting presumptive lens and retina were first drawn by Ida Mann in her series on human eye development( Mann, 1950 ) (see Fig. 1A ). A later TEM study in the rat ( McAvoy, 1980 )identified these processes as holding an abundance of fine filaments. To assess the nature...
Journal Articles
Journal: Development
Development (2008) 135 (5): 799–803.
Published: 01 March 2008
...José Bessa; Maria J. Tavares; Joana Santos; Hiroshi Kikuta; Mary Laplante; Thomas S. Becker; José Luis Gómez-Skarmeta; Fernando Casares During eye development, retinal progenitors are drawn from a multipotent,proliferative cell population. In Drosophila the maintenance of this cell population...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3483–3493.
Published: 01 October 2007
... in the surface ectoderm overlying the optic vesicle, the surrounding mesenchyme and/or presumptive RPE during the initial stages of eye development. During the initial stages of chick eye development the microphthalmia-associated transcription factor( Mitf ), important for RPE development, is expressed...
Journal Articles
Journal: Development
Development (2006) 133 (18): 3651–3660.
Published: 15 September 2006
... required for Xenopus eye development. Kermit 2/XGIPC functions downstream of IGF in eye formation and is required for maintaining IGF-induced AKT activation. A constitutively active PI3 kinase partially rescues the Kermit 2/XGIPC loss-of-function phenotype. Our results provide the first in vivo loss...
Journal Articles
Journal: Development
Development (2006) 133 (2): 351–361.
Published: 15 January 2006
... in the embryonic forebrain by controlling genes of the lateral inhibition pathway. We also investigated the molecular alterations underlying abnormal development of the optic vesicles and Rathke's pouch in Raldh2 -/- mutants. Pax6 is a master gene for eye development (for a review, see Ashery-Padan...
Journal Articles
Journal: Development
Development (2005) 132 (22): 4951–4962.
Published: 15 November 2005
.... Chow, R. L. and Lang, R. A. ( 2001 ). Early eye development in vertebrates. Annu. Rev. Cell Dev. Biol. 17 , 255 -296. Chuang, J. C. and Raymond, P. A. ( 2002 ). Embryonic origin of the eyes in teleost fish. BioEssays 24 , 519 -529. Crossley, P. H., Martinez, S. and Martin, G. R. ( 1996...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (22): 5695–5702.
Published: 15 November 2004
... for correspondence (e-mail: bertrand.mollereau@rockefeller.edu ) 14 9 2004 © 2004. 2004 spalt seven-up Drosophila Planar cell polarity Eye development Planar cell polarity (PCP), also known as tissue polarity, occurs when epithelial cells are polarized along the plane...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2903–2915.
Published: 01 July 2003
... controlling the expression of RPE determinants. At early stages of eye development, the Pax-family member Pax2 is co-expressed with Pax6 in the OV, but is absent in the surface ectoderm ( Nornes et al., 1990 )(this study). During optic nerve formation at ∼E12.5, Pax2 expression becomes restricted...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2939–2951.
Published: 01 July 2003
...Chuen-Chuen Jang; Ju-Lan Chao; Nikolas Jones; Li-Chin Yao; Dmitri A. Bessarab; Yien M. Kuo; Susie Jun; Claude Desplan; Steven K. Beckendorf; Y. Henry Sun We report the identification of a Drosophila Pax gene, eye gone ( eyg ), which is required for eye development. Loss-of-function eyg mutations...
Journal Articles
Journal: Development
Development (2002) 129 (17): 4057–4063.
Published: 01 September 2002
...Matthias Carl; Felix Loosli; Joachim Wittbrodt The establishment of retinal identity and the subsequent patterning of the optic vesicle are the key steps in early vertebrate eye development. To date little is known about the nature and interaction of the genes controlling these steps. So far few...
Journal Articles
Journal: Development
Development (2002) 129 (16): 3795–3802.
Published: 15 August 2002
...., Hofmann, C., Bronckers, A. L., Sohocki, M., Bradley, A. and Karsenty, G. ( 1995 ). BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev . 9 , 2808 -2820. Mabie, P. C., Mehler, M. F. and Kessler, J. A. ( 1999 ). Multiple roles of bone...