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Keywords: Expression
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Journal Articles
Journal: Development
Development (2012) 139 (22): 4210–4219.
Published: 15 November 2012
... defense against micro-organisms and in the pathophysiology of several inflammatory skin diseases. To understand the role of TLRs in the acquisition of immunological competence, we conducted a comprehensive study to evaluate TLR expression and function in the developing human skin before and after birth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (21): 5091–5101.
Published: 1 November 2003
... suggest patterning roles for anterior visceral endoderm (AVE) and ADE. Based on similarity of gene expression patterns, fate and a dual role in`protecting' the prospective forebrain from caudalising influences of the organiser, the chick hypoblast has been suggested to be the homologue of the mouse...
Journal Articles
Journal: Development
Development (2002) 129 (10): 2381–2389.
Published: 15 May 2002
...-containing proteins are involved in Notch signaling in Drosophila and C. elegans via an ectodomain shedding mechanism that depends on a metalloprotease domain. The Dictyostelium protein lacks a metalloprotease domain. Nonetheless, analysis of cell type specific reporter gene expression during development...
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (8): 1715–1728.
Published: 15 April 1999
... have cloned two chick NGNs and found that they are expressed in a subset of neural crest cells early in their migration. Ectopic expression of the NGNs in vivo biases migrating neural crest cells to localize in the sensory ganglia, and induces the expression of sensory neuron-appropriate markers in non...
Journal Articles
Journal: Development
Development (1994) 120 (11): 3083–3092.
Published: 1 November 1994
...Thomas Braun; Eva Bober; Michael A. Rudnicki; Rudolf Jaenisch; Hans-Henning Arnold ABSTRACT The expression pattern of myogenic regulatory factors and myotome-specific contractile proteins was studied during embryonic development of Myf-5 mutant mice by in situ hybridization and immunohistochemistry...
Journal Articles
Journal: Development
Development (1994) 120 (9): 2673–2686.
Published: 1 September 1994
...Kathleen M. George; Mark W. Leonard; Matthew E. Roth; Ken H. Lieuw; Dimitris Kioussis; Frank Grosveld; James Douglas Engel ABSTRACT We describe the embryonic expression pattern as well as the cloning and initial transcriptional regulatory analysis of the murine (m) GATA-3 gene. In situ...
Journal Articles
Journal Articles
Journal: Development
Development (1994) 120 (2): 335–345.
Published: 1 February 1994
...Anna Pavlova; Eugenie Boutin; Gerald Cunha; David Sassoon ABSTRACT We report here that Msx1 (formerly Hox-7 . 1) is expressed at high levels in uterine epithelial cells of the non-pregnant adult. These cells undergo pronounced changes in morphology in response to embryo implantation and show...
Journal Articles
Journal: Development
Development (1994) 120 (2): 301–311.
Published: 1 February 1994
...-2 protein in the developing and adult nervous systems. bcl-2 protein is widespread during embryonic development. Proliferating neuroepithelial cells of ventricular zones as well as the postmitotic cells of the cortical plate, cerebellum, hippocampus and spinal cord express bcl-2. Postnatally, bcl-2...
Journal Articles
Journal: Development
Development (1993) 119 (3): 767–772.
Published: 1 November 1993
...Stephen Small; David N. Arnosti; Michael Levine ABSTRACT The even-skipped ( eve ) promoter contains a series of enhancers that control the expression of different seg-mentation stripes in the Drosophila embryo. The stripe 3 enhancer is located 1.7 kb upstream of the stripe 2 enhancer. Here we...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 114 (1): 261–269.
Published: 1 January 1992
... signal, to initially establish the dorsal-ventral axis of the mesoderm. 28 10 1991 © 1992 by Company of Biologists 1992 Xenopus basic fibroblast growth factor induction mesoderm bFGF expression Determination of both the dorsal-ventral and anterior-posterior embryonic...
Journal Articles
Journal: Development
Development (1990) 110 (3): 733–745.
Published: 1 November 1990
...Juan-Carlos Izpisùa-Belmonte; Pascal Dollé; Armand Renucci; Vincenzo Zappavigna; Hildegard Falkenstein; Denis Duboule We report the cloning, genomic localization, primary structure and developmental expression pattern of the novel mouse Hox-4 . 3 gene. This gene is located within the HOX-4(5...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1989) 106 (2): 399–405.
Published: 1 June 1989
...Erzsebet A. Jonas; Alison M. Snape; Thomas D. Sargent ABSTRACT XK81A1 is a type I epidermal keratin gene expressed in early developmental stages of Xenopus ( Jonas et al . 1985 ). Fusion of the keratin promoter (-5900 to +26) to a human β globin gene led to fully epidermis-specific accumulation...
Journal Articles
Journal: Development
Development (1989) 105 (4): 707–714.
Published: 1 April 1989
...Rashmi Kothary; Susan Clapoff; Susan Darling; Marc D. Perry; Laurence A. Moran; Janet Rossant ABSTRACT Transgenic mice have been generated that express the E. coli β-galactosidase gene under the control of the promoter from the mouse heat-shock gene, hsp68 . Sequences from -664 to +113 relative...
Journal Articles
Journal: Development
Development (1988) 103 (3): 463–471.
Published: 1 July 1988
...B. K. Kay; L. M. Schwartz; U. Rutishauser; T. H. Qiu; H. B. Peng The neural cell adhesion molecule (N-CAM) is seen in the membrane of nerves and muscles from several vertebrate species. Using indirect immunofluorescence, we have examined the expression of this protein during embryonic...
Journal Articles
Journal: Development
Development (1988) 103 (2): 269–277.
Published: 1 June 1988
... tissue of embryos, commencing at the late neural tube stage. Expression is totally dependent on an interaction between mesoderm and ectoderm during gastrulation and can be used as a marker of neural induction. XIF1 shows 94 % homology and XIF3 83 % homology to hamster vimentin at the amino acid level...