... regulation Exencephaly Gastrulation Lung maturation The lysine methylation status of the histone 3 tail is central to epigenetic regulation, pivoting on methylation of lysines at positions 4, 9, 27 and 36. All active RNA polymerase II (Pol II) promoters are characterized by trimethylation...

... weaken the rigidity and cohesion of the neuroepithelium and thus perturb the complex morphogenetic processes taking place during neurulation. Our exencephaly data indicate that Efnb1 +/- are more severely affected than Efnb1 -/- embryos, which has been reported for other phenotypes observed in mice...

... tube and compared with known mouse mutants exhibiting similar defects. * Both authors contributed equally to this work † Author for correspondence 28 07 1994 © 1994 by Company of Biologists 1994 eye skeleton exencephaly dorsal root ganglia motor neurons mouse...